Description

Piconol (Pyridin-2-ylmethanol) is a high-purity organic compound with the molecular formula C₆H₇NO, widely utilized in pharmaceutical synthesis, chemical research, and material science applications. This versatile compound, also known as 2-Pyridinemethanol, features a pyridine ring substituted with a hydroxymethyl group at the 2-position, offering unique reactivity for nucleophilic and catalytic processes. With a CAS number of 586-98-1, our Piconol is rigorously tested to ensure ≥98% purity (HPLC/GC) and is available in scalable quantities for industrial and laboratory use. Suitable for use as a ligand precursor, chiral auxiliary, or intermediate in heterocyclic chemistry, this product is supplied in sealed, light-resistant packaging to maintain stability under recommended storage conditions (2-8°C, inert atmosphere).

Properties

• CAS Number: 586-98-1
• Complexity: 65.5
• IUPAC Name: 2-pyridylmethanol
• InChI: InChI=1S/C6H7NO/c8-5-6-3-1-2-4-7-6/h1-4,8H,5H2
• InChI Key: SHNUBALDGXWUJI-UHFFFAOYSA-N
• Exact Mass: 109.052763847
• Molecular Formula: C6H7NO
• Molecular Weight: 109.13
• SMILES: C1=CC=NC(=C1)CO
• Topological: 33.1
• Monoisotopic Mass: 109.052763847
• Physical Description: Clear hygroscopic liquid;
• Vapor Pressure: 0.02 [mmHg]
• Synonyms: 2-PYRIDINEMETHANOL, pyridin-2-ylmethanol, Piconol, 2-Pyridylmethanol, Pyridine-2-methanol, 2-Pyridyl carbinol, Piconol [INN], Piconolum [Latin], UNII-7HQ8UT1TPS, 7HQ8UT1TPS, EINECS 209-592-7, NSC-760363, BRN 0107849, DTXSID8046531, DTXCID6026531, 5-21-02-00150 (Beilstein Handbook Reference), Piconolum (Latin), NSC 760363, 2pyridylcarbinol, 2pyridylmethanol, Pyridine2carbinol, 2Pyridinylmethanol, 2Pyridyl carbinol, alphaPicolyl alcohol, omegaHydroxy2picoline, 2(Hydroxymethyl)pyridine, inchi=1/c6h7no/c8-5-6-3-1-2-4-7-6/h1-4,8h,5h, shnubaldgxwuji-uhfffaoysa-n, 586-98-1, 2-(Hydroxymethyl)pyridine, 2-Pyridinylmethanol, 2-Pyridylcarbinol, Pyridine-2-carbinol, 2-hydroxymethylpyridine, (Pyridin-2-yl)methanol, MFCD00006348, Pyridin-2-Yl-Methanol, pyridine-methanol, 2-pyridine-methanol, .alpha.-Picolyl alcohol, NCGC00166075-01, alpha-Picolyl alcohol, 2-Pyridine methanol, Piconolum, Pyridinemethanol, CAS-586-98-1, pyridinyl-methanol, 2-pyridinylcarbinol, hydroxymethylpyridine, 2-pyridinyl carbinol, pyridine-2-ylmethanol, 2-pyridylmethan-1-ol, ?-Hydroxy-2-picoline, Pyridine-2-methanol (2-Pyridylcarbinol), pyridine-2-yl-methanol, 2-hydroxymethyl pyridine, 2-hydroxymethyl-pyridine, 2-Pyridinemethanol, 98%, 2-(hydroxymethyl) pyridine, 2-(hydroxymethyl)-pyridine, pyridine, 2-hydroxymethyl-, SCHEMBL29266, SCHEMBL69808, SCHEMBL1383173, SCHEMBL1481683, SCHEMBL1809188, SCHEMBL1924238, SCHEMBL1924707, SCHEMBL1969351, CHEMBL2103981, CHEBI:195070, HMS3264E03, Pharmakon1600-01506166, BCP25788, HY-Y0004, STR00171, Tox21_112305, AC7883, NSC760363, SBB004348, AKOS000249319, Tox21_112305_1, CCG-214048, CS-W020042, FG-0436, FH24411, NCGC00166075-02, SY005684, DB-021521, NS00034000, P0556, EN300-18423, AB01563256_01, AE-641/00340018, SR-01000944286, doi:10.14272/SHNUBALDGXWUJI-UHFFFAOYSA-N.1, SR-01000944286-1, BRD-K28492574-001-01-6, Q27268311, Z57921252, 2-Pyridinylcarbinol;2-Pyridinylmethanol;2-Pyridylcarbinol, F0001-1533

Application

Piconol serves as a key intermediate in the synthesis of pharmaceuticals, particularly for antimalarial and antiviral agents. Its hydroxymethyl group enables facile derivatization for ligand design in transition metal catalysis. Researchers also employ it as a building block for functionalized pyridine derivatives in agrochemical and material science applications.

Safety and Hazards

GHS Hazard Statements

• H302 (87.7%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (98.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (84.2%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (87.7%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (98.2%)
• STOT SE 3 (84.2%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.