Description

2-Amino-5-bromobenzoic acid (CAS No. 5794-88-7) is a high-purity brominated aromatic compound with the molecular formula C₇H₆BrNO₂. This off-white to light brown crystalline powder is a versatile intermediate in organic synthesis, particularly in pharmaceutical and agrochemical research. With a molecular weight of 216.04 g/mol, it features both an amino (-NH₂) and carboxylic acid (-COOH) functional group on a brominated benzene ring, enabling diverse reactivity. Our product is rigorously tested to ensure ≥98% purity (HPLC) and is supplied in sealed containers under inert atmosphere to prevent degradation. Ideal for Suzuki couplings, amide formations, and heterocycle synthesis. Available in research (5g, 25g) and bulk (1kg) quantities with optional COA/MSDS documentation.

Properties

• CAS Number: 5794-88-7
• Complexity: 163
• IUPAC Name: 2-amino-5-bromo-benzoic acid
• InChI: InChI=1S/C7H6BrNO2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,9H2,(H,10,11)
• InChI Key: CUKXRHLWPSBCTI-UHFFFAOYSA-N
• Exact Mass: 214.95819
• Molecular Formula: C7H6BrNO2
• Molecular Weight: 216.03
• SMILES: C1=CC(=C(C=C1Br)C(=O)O)N
• Topological: 63.3
• Monoisotopic Mass: 214.95819
• Physical Description: Solid; Beige powder;
• Synonyms: 2-Amino-5-bromobenzoic acid, 5794-88-7, 5-Bromoanthranilic acid, 4-bromo-2-carboxyaniline, EINECS 227-338-3, BRN 0639028, UNII-Q30190723F, NSC-97201, DTXSID20206643, 4-14-00-01081 (Beilstein Handbook Reference), 5-BROMOANTHRANILIC ACID [MI], NSC 97201, 2Amino5bromobenzoic acid, 5Bromo2aminobenzoic acid, Anthranilic acid, 5bromo, Benzoic acid, 2amino5bromo, DTXCID50129134, cukxrhlwpsbcti-uhfffaoysa-n, inchi=1/c7h6brno2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3h,9h2,(h,10,11, Benzoic acid, 2-amino-5-bromo-, Anthranilic acid, 5-bromo-, 2-Amino-5-bromobenzoicacid, 5-Bromo-2-aminobenzoic acid, MFCD00007823, Q30190723F, 2-amino-5-bromo benzoic acid, 2-amino-5-bromo-benzoic acid, 5-BROMO-2-AMINO-BENZOIC ACID, 5-bromo anthranilic acid, 5-bromo-anthranilic acid, Cambridge id 5121811, MLS000595061, SCHEMBL145485, 2-Aminobenzoic acid, 5-bromo-, CHEMBL1236103, HMS2530F06, NSC97201, STR02291, 2-Amino-5-bromobenzoic acid, 97%, SBB052814, STK298440, AKOS000113100, AC-2470, CS-W009053, FA11428, PS-4918, NCGC00245551-01, SMR000184444, DB-013397, A1254, A8242, NS00033820, ST45024858, EN300-20882, D77697, AH-357/04348043, SR-01000196285, SR-01000196285-1, Q27286937, F1980-0013, Z104484428, SX1

Application

2-Amino-5-bromobenzoic acid serves as a key building block in medicinal chemistry for developing brominated drug candidates, particularly kinase inhibitors and antimicrobial agents. The compound’s orthogonal functional groups enable efficient conversion to benzoxazoles or incorporation into peptidomimetics. Researchers utilize it in palladium-catalyzed cross-coupling reactions to create biaryl structures for material science applications. It also finds use in dye synthesis and as a corrosion inhibitor precursor in specialty coatings.

Safety and Hazards

GHS Hazard Statements

• H301 (79.6%): Toxic if swallowed [Danger Acute toxicity, oral]
• H315 (98.1%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (98.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (96.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 3 (79.6%)
• Skin Irrit. 2 (98.1%)
• Eye Irrit. 2 (98.1%)
• STOT SE 3 (96.3%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.