Description
p-(1-Piperazinyl)phenol (CAS No. 56621-48-8) is a high-purity organic compound with the molecular formula C10H14N2O, widely utilized in pharmaceutical and chemical research. This compound, also known as 4-piperazin-1-ylphenol, features a phenol group linked to a piperazine ring, making it a valuable intermediate in the synthesis of bioactive molecules, including potential drug candidates. With an IUPAC name of 4-piperazin-1-ylphenol, it is characterized by its white to off-white crystalline appearance and high solubility in organic solvents. Our product is rigorously tested for purity and consistency, ensuring optimal performance in research applications. Suitable for laboratory use only.
Properties
- CAS Number: 56621-48-8
- Complexity: 149
- IUPAC Name: 4-piperazin-1-ylphenol
- InChI: InChI=1S/C10H14N2O/c13-10-3-1-9(2-4-10)12-7-5-11-6-8-12/h1-4,11,13H,5-8H2
- InChI Key: GPEOAEVZTOQXLG-UHFFFAOYSA-N
- Exact Mass: 178.110613074
- Molecular Formula: C10H14N2O
- Molecular Weight: 178.23
- SMILES: C1CN(CCN1)C2=CC=C(C=C2)O
- Topological: 35.5
- Monoisotopic Mass: 178.110613074
- Synonyms: 1-(4-Hydroxyphenyl)piperazine, 56621-48-8, p-(1-Piperazinyl)phenol, EINECS 260-289-6, DTXSID80205197, DTXCID80127688, 260-289-6, 4-(piperazin-1-yl)phenol, 4-(1-Piperazinyl)phenol, 4-piperazin-1-ylphenol, N-(4-hydroxyphenyl)piperazine, 4-Piperazinophenol, Phenol, 4-(1-piperazinyl)-, MFCD00066156, 1-(4-Hydroxyphenyl)-piperazine, 4-piperazinylphenol, EN300-17230, 4-(1-piperazino)phenol, 4-Piperazinyl phenol, 4-piperazin-1-yl-phenol, 4-hydroxy phenylpiperazine, 4-piperazine-1-yl-phenol, 4-(piperazine-1-yl)phenol, A2SA24RA7S, 4-(piperazin-1-yl)-phenol, Oprea1_539482, SCHEMBL40343, SCHEMBL662317, 4-(4-hydroxyphenyl)piperazine, SCHEMBL5544384, SCHEMBL6094312, SCHEMBL6094315, 4-HYDROXYPHENYLPIPERAZINE, N-(4-hydroxyphenyl)-piperazine, SCHEMBL15474565, BDBM626043, HMS1786O12, BBL036783, SBB027349, STK585941, AKOS001044007, AC-8984, CS-W017311, FH75439, FS-3772, SY021141, DB-005595, H0891, NS00033553, ST50405636, F14231, 1-(4-Hydroxyphenyl)piperazine, >=98.0% (NT), AE-641/30153018, Z56899148, F2158-0909
Application
p-(1-Piperazinyl)phenol serves as a key intermediate in the synthesis of pharmaceutical compounds, particularly those targeting neurological and cardiovascular disorders. Its structural properties make it useful in the development of serotonin receptor modulators and other bioactive molecules. Researchers also employ this compound in organic synthesis and medicinal chemistry studies to explore novel therapeutic agents.
Safety and Hazards
GHS Hazard Statements
- H314 (10.4%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
- H315 (85.4%): Causes skin irritation [Warning Skin corrosion/irritation]
- H319 (85.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
- H335 (83.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statements
- P260, P261, P264, P264+P265, P271, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P319, P321, P332+P317, P337+P317, P362+P364, P363, P403+P233, P405, and P501
Hazard Classes and Categories
- Skin Corr. 1B (10.4%)
- Skin Irrit. 2 (85.4%)
- Eye Irrit. 2 (85.4%)
- STOT SE 3 (83.3%)
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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.


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