Description

4-Chloro-3-Fluorobenzaldehyde (CAS: 5527-95-7) is a high-purity aromatic aldehyde widely utilized in pharmaceutical, agrochemical, and material science research. This compound, with the molecular formula C₇H₄ClFO, serves as a versatile building block for synthesizing complex organic molecules due to its reactive aldehyde group and halogen substituents. Our product is rigorously tested to ensure ≥97% purity, making it ideal for precision applications in medicinal chemistry, cross-coupling reactions, and ligand synthesis. Packaged under inert conditions to maintain stability, it is supplied as a crystalline solid with minimal moisture content. Suitable for GC/HPLC analysis and lab-scale reactions, this reagent is a critical intermediate for developing novel fluorinated compounds.

Properties

• CAS Number: 5527-95-7
• Complexity: 129
• IUPAC Name: 4-chloro-3-fluoro-benzaldehyde
• InChI: InChI=1S/C7H4ClFO/c8-6-2-1-5(4-10)3-7(6)9/h1-4H
• InChI Key: AZMDWRPTDCIFRD-UHFFFAOYSA-N
• Exact Mass: 157.9934706
• Molecular Formula: C7H4ClFO
• Molecular Weight: 158.56
• SMILES: C1=CC(=C(C=C1C=O)F)Cl
• Topological: 17.1
• Monoisotopic Mass: 157.9934706
• Synonyms: 4-Chloro-3-Fluorobenzaldehyde, 5527-95-7, AZMDWRPTDCIFRD-UHFFFAOYSA-, DTXSID50369316, DTXCID60320352, 627-398-4, azmdwrptdcifrd-uhfffaoysa-n, inchi=1/c7h4clfo/c8-6-2-1-5(4-10)3-7(6)9/h1-4h, 3-fluoro-4-chlorobenzaldehyde, MFCD00143288, Benzaldehyde, 4-chloro-3-fluoro-, 4-chloro-3-fluoro-benzaldehyde, SCHEMBL190947, 4-chloro-3-fluoro benzaldehyde, SCHEMBL2552386, 4-chloranyl-3-fluoranyl-benzaldehyde, CL8343, SBB003986, 4-Chloro-3-Fluorobenzaldehyde, 97%, AKOS005258321, AC-3828, CS-W007521, FC08307, PS-8801, SB40544, SY013909, ST50824716, EN300-55727, A828689, F0001-1449, Z838969200

4-Chloro-3-Fluorobenzaldehyde is extensively used as a key intermediate in the synthesis of pharmaceuticals, particularly for fluorinated drug candidates targeting CNS disorders. It also serves in agrochemical research for developing herbicidal and fungicidal agents. The compound’s halogenated structure facilitates Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (97.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (97.9%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.