Atomfair 2-Chloro-5-iodo-4-methylpyridine C6H5ClIN CAS 550347-54-1

2-Chloro-5-iodo-4-methylpyridine (CAS: 550347-54-1) is a high-purity halogenated pyridine derivative designed for advanced research and industrial applications. This compound, with the molecular formula C6H5ClIN , is a versatile building block in organic synthesis, particularly in pharmaceutical, agrochemical, and material science research. Its unique structure, featuring chloro and iodo substituents on a methylated pyridine ring, enables selective functionalization for the development of novel heterocyclic compounds. Our product is rigorously tested to ensure ≥95% purity (HPLC/GC) and is supplied in moisture-resistant packaging to maintain stability. Available in quantities from milligrams to kilograms, it is ideal for cross-coupling reactions (e.g., Suzuki, Stille), nucleophilic substitutions,…

Description

2-Chloro-5-iodo-4-methylpyridine (CAS: 550347-54-1) is a high-purity halogenated pyridine derivative designed for advanced research and industrial applications. This compound, with the molecular formula C6H5ClIN, is a versatile building block in organic synthesis, particularly in pharmaceutical, agrochemical, and material science research. Its unique structure, featuring chloro and iodo substituents on a methylated pyridine ring, enables selective functionalization for the development of novel heterocyclic compounds. Our product is rigorously tested to ensure ≥95% purity (HPLC/GC) and is supplied in moisture-resistant packaging to maintain stability. Available in quantities from milligrams to kilograms, it is ideal for cross-coupling reactions (e.g., Suzuki, Stille), nucleophilic substitutions, and as a precursor for ligands or catalysts. MSDS and analytical certificates are provided upon request.

Properties

  • CAS Number: 550347-54-1
  • Complexity: 99.1
  • IUPAC Name: 2-chloro-5-iodo-4-methyl-pyridine
  • InChI: InChI=1S/C6H5ClIN/c1-4-2-6(7)9-3-5(4)8/h2-3H,1H3
  • InChI Key: GGKYISVMVRLEDY-UHFFFAOYSA-N
  • Exact Mass: 252.91552
  • Molecular Formula: C6H5ClIN
  • Molecular Weight: 253.47
  • SMILES: CC1=CC(=NC=C1I)Cl
  • Topological: 12.9
  • Monoisotopic Mass: 252.91552
  • Synonyms: 2-chloro-5-iodo-4-methylpyridine, 550347-54-1, DTXSID20679732, DTXCID40630481, 867-310-3, MFCD13185454, 2-chloro-5-iodo-4-methyl-pyridine, SCHEMBL15508004, GGKYISVMVRLEDY-UHFFFAOYSA-N, 5-Iodo-2-chloro-4-methylpyridine, AKOS015891498, AC-27535, DS-18360, SY032483, DB-071934, CS-0097905, EN300-250541, I11185

2-Chloro-5-iodo-4-methylpyridine serves as a key intermediate in medicinal chemistry for synthesizing bioactive molecules targeting kinase inhibition or CNS disorders. Its halogenated pyridine core is utilized in palladium-catalyzed cross-couplings to construct complex architectures in drug discovery. The compound also finds use in materials science for developing photoactive polymers and as a directing group in metal-organic frameworks (MOFs).

Safety and Hazards

GHS Hazard Statements

  • H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
  • H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]
  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]
  • H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Acute Tox. 4 (100%)
  • Acute Tox. 4 (100%)
  • Skin Irrit. 2 (100%)
  • Eye Irrit. 2A (100%)
  • Acute Tox. 4 (100%)
  • STOT SE 3 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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