Atomfair 5-Amino-4,6-dichloropyrimidine C4H3Cl2N3 CAS 5413-85-4

Description

5-Amino-4,6-dichloropyrimidine (CAS No. 5413-85-4) is a high-purity heterocyclic organic compound with the molecular formula C₄H₃Cl₂N₃. This chlorinated pyrimidine derivative is a versatile building block in pharmaceutical and agrochemical synthesis, particularly for nucleoside analogs and active pharmaceutical ingredients (APIs). Its IUPAC name, 4,6-dichloropyrimidin-5-amine, reflects its precise chemical structure featuring reactive amino and chloro substituents. Supplied as a crystalline solid with ≥98% purity (HPLC), it is rigorously tested for consistency, stability, and low heavy metal content. Ideal for medicinal chemistry research, this compound is packaged under inert gas in amber glass vials to ensure long-term stability. Available in quantities from grams to kilograms with optional custom purity and packaging specifications.

Properties

• CAS Number: 5413-85-4
• Complexity: 89.8
• IUPAC Name: 4,6-dichloropyrimidin-5-amine
• InChI: InChI=1S/C4H3Cl2N3/c5-3-2(7)4(6)9-1-8-3/h1H,7H2
• InChI Key: NIGDWBHWHVHOAD-UHFFFAOYSA-N
• Exact Mass: 162.9704025
• Molecular Formula: C4H3Cl2N3
• Molecular Weight: 163.99
• SMILES: C1=NC(=C(C(=N1)Cl)N)Cl
• Topological: 51.8
• Monoisotopic Mass: 162.9704025
• Synonyms: 5-Amino-4,6-dichloropyrimidine, 5413-85-4, 5-Pyrimidinamine, 4,6-dichloro-, 4,6-Dichloro-5-pyrimidinamine, NSC 7851, EINECS 226-503-7, AI3-52090, DTXSID6063850, DTXCID9041609, nigdwbhwhvhoad-uhfffaoysa-n, 4,6-dichloropyrimidin-5-amine, 4,6-Dichloro-5-aminopyrimidine, 4,6-Dichloropyrimidin-5-ylamine, 4,6-dichloro-pyrimidin-5-ylamine, MFCD00006108, Pyrimidine, 5-amino-4,6-dichloro-, 4,6-dichloropyrimidine-5-ylamine, 5-amine-4,6-dichloropyrimidine, NSC7851, SCHEMBL41301, 5-Pyrimidinamine,6-dichloro-, SCHEMBL4054045, 4,6-dichloropyrimidine-5-amine, CHEMBL2151974, 4, 6-dichloro-5-aminopyrimidine, 5-amino-4,6-dichloro pyrimidine, 5-amino-4,6-dichloro-pyrimidine, (4,6-dichloropyrimidin-5-yl)amine, 4,6-dichloro-pyrimidin-5-yl-amine, ALBB-025594, BCP19480, NSC-7851, SBB003920, AKOS000280684, AB00590, AC-3095, CS-W001987, FA11123, GS-6845, HY-W001987, 5-Amino-4,6-dichloropyrimidine, 97%, BP-12042, SY003819, DB-006947, A1395, NS00032968, ST45028570, EN300-29203, AB-323/25048131, Z276572864

Application

5-Amino-4,6-dichloropyrimidine serves as a key intermediate in the synthesis of antiviral and anticancer nucleoside analogs. Its reactive sites enable efficient functionalization for creating pyrimidine-based scaffolds in drug discovery. Researchers utilize it in cross-coupling reactions to develop novel heterocyclic compounds for pharmaceutical applications. The compound is also employed in agrochemical research for designing crop protection agents.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (98%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (98%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.