Atomfair 4-Amino-3-(4-fluorophenyl)butanoic acid [‘4-Fluorophenibut’, ‘Cgp 11130’] C10H12FNO2 CAS 52237-19-1

Description

4-Amino-3-(4-fluorophenyl)butanoic acid (CAS No. 52237-19-1) is a fluorinated derivative of the well-known GABA analog phenibut, with the molecular formula C₁₀H₁₂FNO₂. This high-purity compound is synthesized for advanced research applications, particularly in neuroscience and pharmacology. The addition of a fluorine atom at the para position of the phenyl ring enhances its potential metabolic stability and bioavailability, making it a valuable tool for studying GABA_B receptor interactions. Our product is rigorously tested by HPLC and NMR to ensure ≥98% purity, supplied as a white to off-white crystalline powder under inert packaging to maintain stability. Ideal for structure-activity relationship (SAR) studies, this compound is available in research quantities from milligrams to grams with custom bulk options.

Properties

• CAS Number: 52237-19-1
• Complexity: 191
• IUPAC Name: 4-amino-3-(4-fluorophenyl)butanoic acid
• InChI: InChI=1S/C10H12FNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)
• InChI Key: QWHXHLDNSXLAPX-UHFFFAOYSA-N
• Exact Mass: 197.08520679
• Molecular Formula: C10H12FNO2
• Molecular Weight: 197.21
• SMILES: C1=CC(=CC=C1C(CC(=O)O)CN)F
• Topological: 63.3
• Monoisotopic Mass: 197.08520679
• Synonyms: 52237-19-1, 4-amino-3-(4-fluorophenyl)butanoic acid, 4-Amino-3-(4-fluoro-phenyl)-butyric acid, 4-Fluorophenibut, Cgp 11130, 6DAU7M5P3D, Cgp-11130, 4-Amino-3-(4-fluorophenyl)butyric acid, Benzenepropanoic acid, beta-(aminomethyl)-4-fluoro-, (R)- (9CI), Benzenepropanoic acid, beta-(aminomethyl)-4-fluoro-, (S)- (9CI), Cgp-11.130, Benzenepropanoic acid, beta-(aminomethyl)-4-fluoro-, UNII-6DAU7M5P3D, SCHEMBL351502, DTXSID00966612, MFCD14551310, AKOS014313413, AS-18059, EN300-705920

Application

4-Amino-3-(4-fluorophenyl)butanoic acid is primarily used in neuroscience research as a fluorinated analog of phenibut to investigate GABA_B receptor modulation. Its structural modification allows for comparative studies on blood-brain barrier penetration and metabolic pathways. Researchers utilize this compound in SAR analyses to explore the impact of aromatic fluorination on neuropharmacological activity. It may also serve as a precursor for novel CNS-active compounds in medicinal chemistry programs.

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.