Description

2-Chloro-1-(2,4-difluorophenyl)ethanone (CAS No. 51336-94-8) is a high-purity organic compound with the molecular formula C₈H₅ClF₂O. This halogenated aromatic ketone is a versatile building block in synthetic organic chemistry, particularly in pharmaceutical and agrochemical research. Its unique structure, featuring both chloro and difluoro substituents, makes it a valuable intermediate for the synthesis of complex molecules. Our product is rigorously tested to ensure ≥98% purity (HPLC/GC) and is supplied in sealed, light-resistant containers to maintain stability. Ideal for nucleophilic substitution reactions, cross-coupling reactions, and as a precursor for heterocyclic compounds.

Properties

• CAS Number: 51336-94-8
• Complexity: 174
• IUPAC Name: 2-chloro-1-(2,4-difluorophenyl)ethanone
• InChI: InChI=1S/C8H5ClF2O/c9-4-8(12)6-2-1-5(10)3-7(6)11/h1-3H,4H2
• InChI Key: UENGBOCGGKLVJJ-UHFFFAOYSA-N
• Exact Mass: 189.9996988
• Molecular Formula: C8H5ClF2O
• Molecular Weight: 190.57
• SMILES: C1=CC(=C(C=C1F)F)C(=O)CCl
• Topological: 17.1
• Monoisotopic Mass: 189.9996988
• Synonyms: 51336-94-8, 2-Chloro-1-(2,4-difluorophenyl)ethanone, UENGBOCGGKLVJJ-UHFFFAOYSA-, 620-343-5, inchi=1/c8h5clf2o/c9-4-8(12)6-2-1-5(10)3-7(6)11/h1-3h,4h2, 2-Chloro-2′,4′-difluoroacetophenone, 2,4-Difluorophenacyl Chloride, 2-Chloro-2,4-difluoroacetophenone, MFCD00013252, CHEMBL105349, 1-(2,4-difluorophenyl)-2-chloroethan-1-one, 2-Chloro-1-(2,4-difluoro-phenyl)-ethanone, 2-Chloro-1-(2,4-Difluorophenyl)Ethan-1-One, 2′,4′-DIFLUORO-2-CHLOROACETOPHENONE, 2′,4′-DIFLUOROPHENACYL CHLORIDE, Ethanone, 2-chloro-1-(2,4-difluorophenyl)-, 2-Chloro-2, ALPHA-CHLORO-2,4-DIFLUOROACETOPHENONE, SCHEMBL2597507, SCHEMBL28126593, DTXSID40343185, BCP20884, BDBM50119690, SBB006665, STK399765, 2,4-difluoro-alpha-chloroacetophenone, AKOS000200625, 2-chloro-2′, 4′-difluoroacetophenone, 2-Chloro-2′,4′-difluoro Acetophenone, AC-1571, CS-W015868, FC20008, UPCMLD0ENAT5630404:001, 2-Chloro-2′,4′-difluoroacetophenone, NCGC00660495-01, 1-(2,4-difluorophenyl)-2-chloroethanone, PD140505, PS-11647, 2-chloro-1-(2,4-difluorophenyl)-ethanone, DB-019943, 2-chloro-1(2,4-difluorophenyl)-1-ethanone, 2-Chloro-1-(2,4-difluorophenyl)ethanone #, 2-Chloro-2′,4′-difluoroacetophenone, 98%, A7574, C2030, NS00077456, ST50585865, EN300-22218, F0001-1340, Z147642150, 2-CHLORO-1-(2,4-DIFLUOROPHENYL)ETHANONE 2′-CHLORO-2,4-DIFLUOROACETOPHENONE 2-CHLORO-2′,4′-DIFLUOROACETOPHENONE 2′,4, 2-Chloro-1-(2,4-difluorophenyl)ethanone;Chloromethyl 2,4-difluorophenyl ketone;a-Chloro-2,4-difluoroacetophenone

Application

2-Chloro-1-(2,4-difluorophenyl)ethanone is widely used as a key intermediate in the synthesis of antifungal and antibacterial agents. Its reactive chloroacetyl group enables efficient derivatization for drug discovery programs targeting infectious diseases. Researchers also employ this compound in the development of fluorinated liquid crystals and advanced materials. In agrochemistry, it serves as a precursor for crop protection agents.

Safety and Hazards

GHS Hazard Statements

• H314 (98%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

Precautionary Statements

• P260, P264, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P363, P405, and P501

Hazard Classes and Categories

• Skin Corr. 1B (98%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.