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Atomfair 3-Bromo-5-methylpyridine-2-carbonitrile C7H5BrN2 CAS 474824-78-7

3-Bromo-5-methylpyridine-2-carbonitrile (CAS No. 474824-78-7) is a high-purity heterocyclic organic compound with the molecular formula C7H5BrN2. This brominated pyridine derivative is a versatile building block in pharmaceutical and agrochemical synthesis, offering excellent reactivity for cross-coupling reactions, nucleophilic substitutions, and cyanation transformations. Its molecular weight of 197.03 g/mol and precise structure make it ideal for medicinal chemistry research, particularly in the development of kinase inhibitors and other bioactive molecules. The compound is supplied as a crystalline solid with ≥95% purity (HPLC), ensuring consistent performance in synthetic applications. Proper storage at 2-8°C in a tightly sealed container under inert atmosphere is recommended to…

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Description

3-Bromo-5-methylpyridine-2-carbonitrile (CAS No. 474824-78-7) is a high-purity heterocyclic organic compound with the molecular formula C7H5BrN2. This brominated pyridine derivative is a versatile building block in pharmaceutical and agrochemical synthesis, offering excellent reactivity for cross-coupling reactions, nucleophilic substitutions, and cyanation transformations. Its molecular weight of 197.03 g/mol and precise structure make it ideal for medicinal chemistry research, particularly in the development of kinase inhibitors and other bioactive molecules. The compound is supplied as a crystalline solid with ≥95% purity (HPLC), ensuring consistent performance in synthetic applications. Proper storage at 2-8°C in a tightly sealed container under inert atmosphere is recommended to maintain stability.

Properties

  • CAS Number: 474824-78-7
  • Complexity: 160
  • IUPAC Name: 3-bromo-5-methyl-pyridine-2-carbonitrile
  • InChI: InChI=1S/C7H5BrN2/c1-5-2-6(8)7(3-9)10-4-5/h2,4H,1H3
  • InChI Key: WGKYSFRFMQHMOF-UHFFFAOYSA-N
  • Exact Mass: 195.96361
  • Molecular Formula: C7H5BrN2
  • Molecular Weight: 197.03
  • SMILES: CC1=CC(=C(N=C1)C#N)Br
  • Topological: 36.7
  • Monoisotopic Mass: 195.96361
  • Synonyms: 474824-78-7, 3-Bromo-5-methylpyridine-2-carbonitrile, DTXSID70626655, DTXCID40577408, 807-909-9, 3-bromo-5-methylpicolinonitrile, 3-Bromo-2-cyano-5-methylpyridine, MFCD16988815, SCHEMBL1008431, WGKYSFRFMQHMOF-UHFFFAOYSA-N, AKOS015835081, CS-W021873, FS-3330, BL007503, SY031477, EN300-172706

Application

3-Bromo-5-methylpyridine-2-carbonitrile serves as a key intermediate in the synthesis of pharmaceutical compounds, particularly for creating pyridine-based drug candidates. Its reactive bromine and nitrile groups enable efficient participation in Suzuki, Stille, and other palladium-catalyzed coupling reactions. Researchers utilize this compound in developing potential treatments for neurological disorders and inflammatory diseases due to its ability to modulate biological targets. The methyl group at the 5-position offers additional opportunities for functionalization in medicinal chemistry workflows.

Safety and Hazards

GHS Hazard Statements

  • H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
  • H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]
  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]
  • H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Acute Tox. 4 (100%)
  • Acute Tox. 4 (100%)
  • Skin Irrit. 2 (100%)
  • Eye Irrit. 2 (100%)
  • Acute Tox. 4 (100%)
  • STOT SE 3 (100%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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