Description

2,3-Difluoroaniline (CAS No. 4519-40-8) is a high-purity fluorinated aromatic amine with the molecular formula C₆H₅F₂N. This compound is a valuable building block in organic synthesis, particularly in the pharmaceutical and agrochemical industries. Its IUPAC name is 2,3-difluoroaniline, and it is characterized by the presence of two fluorine atoms at the 2 and 3 positions of the aniline ring, which enhances its reactivity and utility in cross-coupling reactions. Available in liquid form, this reagent is rigorously tested for purity and stability, ensuring consistent performance in demanding applications. Proper storage under inert conditions is recommended to maintain its integrity.

Properties

• CAS Number: 4519-40-8
• Complexity: 97.1
• IUPAC Name: 2,3-difluoroaniline
• InChI: InChI=1S/C6H5F2N/c7-4-2-1-3-5(9)6(4)8/h1-3H,9H2
• InChI Key: YCCQGFYAVUTQFK-UHFFFAOYSA-N
• Exact Mass: 129.03900549
• Molecular Formula: C6H5F2N
• Molecular Weight: 129.11
• SMILES: C1=CC(=C(C(=C1)F)F)N
• Topological: 26
• Monoisotopic Mass: 129.03900549
• Synonyms: 2,3-Difluoroaniline, 4519-40-8, Benzenamine, 2,3-difluoro-, EINECS 224-847-2, YCCQGFYAVUTQFK-UHFFFAOYSA-, DTXSID80196415, DTXCID90118906, 224-847-2, inchi=1/c6h5f2n/c7-4-2-1-3-5(9)6(4)8/h1-3h,9h2, yccqgfyavutqfk-uhfffaoysa-n, 2,3-difluorobenzenamine, 2,3-difluorophenylamine, MFCD00010298, 2,3-Difluoro-phenylamine, difluoraniline, 2,3-difluorophenyl amine, Aniline, 2,3-difluoro-, PZ3T7X9RBZ, SCHEMBL59477, 2,3-Difluoroaniline, 98%, BIDD:GT0108, SCHEMBL2967149, SCHEMBL3004021, SCHEMBL5510055, SCHEMBL27199257, BCP10332, SBB006565, AKOS005259161, AC-2725, CS-W007344, FD64332, PS-9154, SY002696, DB-024052, D2595, NS00045821, ST51038106, EN300-52525, F0001-1224, Z755885564

Application

2,3-Difluoroaniline is widely used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. Its fluorinated aromatic structure makes it a key precursor for the development of active ingredients in drugs and pesticides. Researchers also utilize it in the preparation of liquid crystals and advanced materials. Its reactivity in electrophilic substitution and coupling reactions is highly valued in organic chemistry.

Safety and Hazards

GHS Hazard Statements

• H302 (95.8%): Harmful if swallowed [Warning Acute toxicity, oral]
• H311 (12.5%): Toxic in contact with skin [Danger Acute toxicity, dermal]
• H312 (87.5%): Harmful in contact with skin [Warning Acute toxicity, dermal]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H331 (12.5%): Toxic if inhaled [Danger Acute toxicity, inhalation]
• H332 (87.5%): Harmful if inhaled [Warning Acute toxicity, inhalation]
• H335 (89.6%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P262, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P316, P317, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (95.8%)
• Acute Tox. 3 (12.5%)
• Acute Tox. 4 (87.5%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• Acute Tox. 3 (12.5%)
• Acute Tox. 4 (87.5%)
• STOT SE 3 (89.6%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.