Get FREE SHIPPING when you spend $99 or more | ATOMFAIR

Awaiting product image

Atomfair 2-Chloro-5-iodo-3-nitropyridine C5H2ClIN2O2 CAS 426463-05-0

2-Chloro-5-iodo-3-nitropyridine (CAS No. 426463-05-0) is a high-purity halogenated nitropyridine compound with the molecular formula C5H2ClIN2O2. This heterocyclic aromatic compound is characterized by its chloro, iodo, and nitro functional groups, making it a versatile intermediate for organic synthesis and pharmaceutical research. With a molecular weight of 284.44 g/mol, it is supplied as a crystalline solid with >95% purity (HPLC). Ideal for cross-coupling reactions, nucleophilic substitutions, and as a precursor for agrochemicals or drug discovery. Store in a cool, dry place under inert conditions to ensure stability.

Category:

Description

2-Chloro-5-iodo-3-nitropyridine (CAS No. 426463-05-0) is a high-purity halogenated nitropyridine compound with the molecular formula C5H2ClIN2O2. This heterocyclic aromatic compound is characterized by its chloro, iodo, and nitro functional groups, making it a versatile intermediate for organic synthesis and pharmaceutical research. With a molecular weight of 284.44 g/mol, it is supplied as a crystalline solid with >95% purity (HPLC). Ideal for cross-coupling reactions, nucleophilic substitutions, and as a precursor for agrochemicals or drug discovery. Store in a cool, dry place under inert conditions to ensure stability.

Properties

  • CAS Number: 426463-05-0
  • Complexity: 163
  • IUPAC Name: 2-chloro-5-iodo-3-nitro-pyridine
  • InChI: InChI=1S/C5H2ClIN2O2/c6-5-4(9(10)11)1-3(7)2-8-5/h1-2H
  • InChI Key: PIJMRJPJERUFNI-UHFFFAOYSA-N
  • Exact Mass: 283.88495
  • Molecular Formula: C5H2ClIN2O2
  • Molecular Weight: 284.44
  • SMILES: C1=C(C=NC(=C1[N+](=O)[O-])Cl)I
  • Topological: 58.7
  • Monoisotopic Mass: 283.88495
  • Synonyms: 2-Chloro-5-iodo-3-nitropyridine, 426463-05-0, DTXSID50363839, DTXCID50314886, 686-984-8, 2-chloro-5-iodo-3-nitro-pyridine, MFCD04038568, SCHEMBL1600705, 5-iodo-3-nitro-2-chloropyridine, PIJMRJPJERUFNI-UHFFFAOYSA-N, GEO-03609, AKOS016007130, CS-W020533, DS-2552, PB26113, 2-Chloro-5-iodo-3-nitropyridine, 97%, 2-Chloro-5-iodo-3-nitropyridine, 98%, AC-27506, SY096986, DB-081219, C30180, EN300-103316

Application

2-Chloro-5-iodo-3-nitropyridine serves as a key building block in medicinal chemistry for the synthesis of bioactive molecules, particularly kinase inhibitors and antimicrobial agents. Its reactive halogen and nitro groups facilitate Suzuki-Miyaura and Buchwald-Hartwig couplings in pharmaceutical R&D. The compound is also employed in material science for designing nitrogen-rich heterocyclic frameworks.

Safety and Hazards

GHS Hazard Statements

  • H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
  • H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Acute Tox. 4 (100%)
  • Skin Irrit. 2 (100%)
  • Eye Dam. 1 (100%)
  • STOT SE 3 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.

Related products