Description

1,2,3,4-Tetrahydroisoquinoline carboxylic acid (CAS: 41034-52-0) is a high-purity organic compound with the molecular formula C₁₀H₁₁NO₂. This versatile heterocyclic carboxylic acid is widely used in pharmaceutical research, medicinal chemistry, and as a key intermediate in the synthesis of bioactive molecules. Our product is rigorously tested to ensure >98% purity by HPLC, making it ideal for demanding applications in drug discovery and biochemical studies. The compound is supplied as a white to off-white crystalline powder with excellent solubility in common organic solvents. Each batch is accompanied by comprehensive analytical data including NMR, MS, and HPLC chromatograms to guarantee quality and consistency for your research needs.

Properties

• CAS Number: 41034-52-0
• Complexity: 205
• IUPAC Name: 1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid
• InChI: InChI=1S/C10H11NO2/c12-10(13)9-8-4-2-1-3-7(8)5-6-11-9/h1-4,9,11H,5-6H2,(H,12,13)
• InChI Key: OXFGRWIKQDSSLY-UHFFFAOYSA-N
• Exact Mass: 177.078978594
• Molecular Formula: C10H11NO2
• Molecular Weight: 177.20
• SMILES: C1CNC(C2=CC=CC=C21)C(=O)O
• Topological: 49.3
• Monoisotopic Mass: 177.078978594
• Synonyms: 41034-52-0, THIQC, 1-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-, Tetrahydroisoquinoline carboxylic acid, 1,2,3,4-Tetrahydroisoquinoline carboxylic acid, L-Tetrahydro-3-isoquinoline carboxylic acid, tetrahydroisoquinoline-3-carboxylate, 1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid, 1,2,3,4-Tetrahydro-isoquinoline-1-carboxylic acid, 1,2,3,4-TETRAHYDRO-1-ISOQUINOLINECARBOXYLIC ACID, MFCD01318704, 1,2,3,4-tetrahydroisoquinolinecarboxylic acid, MFCD03426332, CBMicro_037756, ChemDiv2_002122, SCHEMBL514422, SCHEMBL1388248, CHEMBL1616107, SCHEMBL11654912, OXFGRWIKQDSSLY-UHFFFAOYSA-N, DTXSID001347435, HMS1375A10, ALBB-018657, SBB000197, STK675636, AKOS000601652, AKOS016344053, AB08729, AB14827, AB14831, FS-2257, SDCCGMLS-0013674.P002, tetrahydroisoquinoline-1-carboxylic acid, AC-29612, ST028624, SY018413, SY020682, SY038411, DB-012690, DB-043073, DB-043074, CS-0005330, EN300-56240, T11200, 1,2,3,4-tetrahydroisoquinolin-1-carboxylic acid, 1,2,3,4-Tetrahydro-1-isoquinoline carboxylic acid, (+/-)-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid, 1-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-, hydrochloride

1,2,3,4-Tetrahydroisoquinoline carboxylic acid serves as a crucial building block in the synthesis of various pharmaceutical compounds, particularly those targeting neurological disorders. Researchers utilize this compound in the development of opioid receptor ligands and enzyme inhibitors. Its structural features make it valuable for creating constrained peptide mimetics in drug design. The carboxylic acid functionality allows for further derivatization through amide coupling or esterification reactions. This intermediate is particularly important in medicinal chemistry programs focusing on CNS-active molecules.

Safety and Hazards

GHS Hazard Statements

• H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (50%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (50%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (50%)
• Skin Irrit. 2 (50%)
• Eye Irrit. 2 (50%)
• STOT SE 3 (50%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.