Description

2-Fluoro-6-methylpyridine (CAS No. 407-22-7) is a high-purity fluorinated pyridine derivative with the molecular formula C₆H₆FN. This specialized organic compound is characterized by a fluorine substituent at the 2-position and a methyl group at the 6-position of the pyridine ring, offering unique reactivity and steric properties. It is an essential intermediate in pharmaceutical synthesis, agrochemical development, and advanced material science applications. Available in >98% purity (GC), our product is rigorously tested to meet the stringent requirements of research and industrial processes. Packaged under inert gas to ensure stability, it is supplied in amber glass bottles or custom bulk quantities to suit your laboratory needs.

Properties

• CAS Number: 407-22-7
• Complexity: 74.9
• IUPAC Name: 2-fluoro-6-methyl-pyridine
• InChI: InChI=1S/C6H6FN/c1-5-3-2-4-6(7)8-5/h2-4H,1H3
• InChI Key: UDMNVTJFUISBFD-UHFFFAOYSA-N
• Exact Mass: 111.048427358
• Molecular Formula: C6H6FN
• Molecular Weight: 111.12
• SMILES: CC1=NC(=CC=C1)F
• Topological: 12.9
• Monoisotopic Mass: 111.048427358
• Synonyms: 2-Fluoro-6-methylpyridine, 407-22-7, Pyridine, 2-fluoro-6-methyl-, EINECS 206-980-8, DTXSID50193673, NSC 51590, DTXCID90116164, 206-980-8, udmnvtjfuisbfd-uhfffaoysa-n, 6-Fluoro-2-picoline, 2-fluoro-6-methyl-pyridine, MFCD00041226, 2-fluoro-6-picoline, 6-fluoro-2-methylpyridine, 2-methyl-6-fluoro-pyridine, NSC51590, 2-fluoro-6-methylpyridin, 2-Fluoro-6-methylpyridine (2-Fluoro-6-picoline), SCHEMBL45846, SCHEMBL1724717, SCHEMBL1949175, SCHEMBL2068735, 2-Fluoro-6-methylpyridine, 97%, BCP22133, NSC-51590, AKOS005063645, AB01860, CS-W013665, PS-9256, AC-23603, SY014114, DB-031388, F0520, NS00043269, EN300-86549, D70847, 6-Bromo-2-(di(tert-butoxycarbonyl)aminopyridine, 6-Fluoro-2-picoline;Pyridine, 2-fluoro-6-methyl-

Application

2-Fluoro-6-methylpyridine serves as a versatile building block in medicinal chemistry for the synthesis of fluorinated drug candidates, particularly in kinase inhibitor development. Its electron-withdrawing fluorine atom enhances binding affinity in bioactive molecules, while the methyl group allows for further functionalization. The compound is also employed in ligand design for catalysis and as a precursor for fluorinated liquid crystals in display technologies.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (98%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (98%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.