Description

N-p-Bromophenylphthalimide (CAS No. 40101-31-3) is a high-purity brominated aromatic compound with the molecular formula C₁₄H₈BrNO₂. This crystalline solid, also known by its IUPAC name 2-(4-bromophenyl)isoindole-1,3-dione, is a valuable intermediate in organic synthesis and pharmaceutical research. With a molecular weight of 302.12 g/mol, it features a phthalimide core functionalized with a para-bromophenyl group, offering unique reactivity for cross-coupling reactions and heterocyclic chemistry. Our product is rigorously tested for purity (>98% by HPLC) and is supplied as a fine, off-white powder with excellent batch-to-batch consistency. Suitable for research scale applications, it is packaged under inert atmosphere to ensure stability and long shelf life. Ideal for use in Suzuki-Miyaura couplings, Buchwald-Hartwig aminations, and as a precursor for advanced materials.

Properties

• CAS Number: 40101-31-3
• Complexity: 339
• IUPAC Name: 2-(4-bromophenyl)isoindoline-1,3-dione
• InChI: InChI=1S/C14H8BrNO2/c15-9-5-7-10(8-6-9)16-13(17)11-3-1-2-4-12(11)14(16)18/h1-8H
• InChI Key: DNQCPYWSXMATIN-UHFFFAOYSA-N
• Exact Mass: 300.97384
• Molecular Formula: C14H8BrNO2
• Molecular Weight: 302.12
• SMILES: C1=CC=C2C(=C1)C(=O)N(C2=O)C3=CC=C(C=C3)Br
• Topological: 37.4
• Monoisotopic Mass: 300.97384
• Synonyms: N-(4-Bromophenyl)phthalimide, 40101-31-3, N-(p-Bromophenyl)phthalimide, N-p-Bromophenylphthalimide, Phthalimide, N-(p-bromophenyl)-, NSC 406153, BRN 0189461, Q5563GUU8L, 1H-Isoindole-1,3(2H)-dione, 2-(4-bromophenyl)-, AI3-01400, 2-(4-bromophenyl)-1H-isoindole-1,3(2H)-dione, NSC-406153, DTXSID80193146, 5-21-10-00294 (Beilstein Handbook Reference), DTXCID90115637, 678-166-4, 2-(4-bromophenyl)isoindoline-1,3-dione, 2-(4-Bromophenyl)isoindole-1,3-dione, 2-(4-bromophenyl)-2,3-dihydro-1H-isoindole-1,3-dione, MFCD00047301, NSC406153, UNII-Q5563GUU8L, N-(4-bromophenyl)-phthalimide, SCHEMBL3619832, DNQCPYWSXMATIN-UHFFFAOYSA-, Phthalimide, N-(p-bromo-phenyl)-, STK266230, AKOS000175151, SB64095, 1H-Isoindole-1, 2-(4-bromophenyl)-, AS-63649, B2707, CS-0182188, ST50332516, 2-(4-bromophenyl)benzo[c]azoline-1,3-dione, D88952, InChI=1/C14H8BrNO2/c15-9-5-7-10(8-6-9)16-13(17)11-3-1-2-4-12(11)14(16)18/h1-8H

Application

N-p-Bromophenylphthalimide serves as a versatile building block in medicinal chemistry for the synthesis of pharmaceutically active compounds. It is particularly useful in the development of kinase inhibitors and other small molecule therapeutics due to its bromine handle for further functionalization. Researchers utilize this compound in material science for creating organic semiconductors and photoactive materials. The phthalimide moiety also makes it valuable for polymer modification and as a precursor for fluorescent dyes.

Safety and Hazards

GHS Hazard Statements

• H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

Precautionary Statements

• P264, P270, P301+P317, P330, and P501

Hazard Classes and Categories

• Acute Tox. 4 (100%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.