Description

2-Chloro-4-trifluoromethylaniline (CAS No. 39885-50-2) is a high-purity aromatic amine derivative with the molecular formula C₇H₅ClF₃N. This compound, also known by its IUPAC name 2-chloro-4-(trifluoromethyl)aniline, is a versatile intermediate widely used in organic synthesis, pharmaceuticals, and agrochemical research. Its unique structure, featuring both chloro and trifluoromethyl functional groups, makes it a valuable building block for designing advanced molecules with tailored properties.

Our product is rigorously tested to ensure >98% purity (HPLC/GC), with strict quality control to minimize impurities. It is supplied as a crystalline solid or powder, packaged under inert conditions to ensure stability. Suitable for use in nucleophilic substitutions, cross-coupling reactions, and as a precursor for heterocyclic compounds. Available in research (gram) to bulk (kilogram) quantities with customizable packaging options.

Properties

• CAS Number: 39885-50-2
• Complexity: 159
• IUPAC Name: 2-chloro-4-(trifluoromethyl)aniline
• InChI: InChI=1S/C7H5ClF3N/c8-5-3-4(7(9,10)11)1-2-6(5)12/h1-3H,12H2
• InChI Key: MBBUTABXEITVNY-UHFFFAOYSA-N
• Exact Mass: 195.0062613
• Molecular Formula: C7H5ClF3N
• Molecular Weight: 195.57
• SMILES: C1=CC(=C(C=C1C(F)(F)F)Cl)N
• Topological: 26
• Monoisotopic Mass: 195.0062613
• Synonyms: 39885-50-2, 2-Chloro-4-trifluoromethylaniline, BENZENAMINE, 2-CHLORO-4-(TRIFLUOROMETHYL)-, D67KX3WQ3Z, 2-chloro-4-(trifluoromethyl)benzenamine, EINECS 254-674-8, DTXSID30192922, Cl-TFMA, DTXCID70115413, 254-674-8, 2-Chloro-4-(trifluoromethyl)aniline, 4-Amino-3-chlorobenzotrifluoride, MFCD00042563, 2-chloro-4-(trifluoromethyl)phenylamine, haloaniline, 3-chloro-4-aminobenzotrifluoride, tau-fluvalinate TP2, 2-Chloro-4-trifluoromethyl-phenylamine, UNII-D67KX3WQ3Z, SCHEMBL119351, SCHEMBL11101764, SCHEMBL28220138, 2-chloro-4-trifluoromethyaniline, CHEBI:194659, 2-chloro-4-(triluoromethyl)aniline, SBB003594, AKOS000121449, AC-2323, CS-W019542, PS-8280, 2-Chloro-4-(trifluoromethyl)aniline, 97%, DB-020797, A1511, A6655, NS00057317, ST50405237, EN300-21172, F0001-1121, Z104493462, 4-Amino-3-chlorobenzotrifluoride;2-Chloro-4-trifluoromethylaniline

Application

2-Chloro-4-trifluoromethylaniline serves as a key intermediate in the synthesis of pharmaceuticals, particularly for antitumor and antimicrobial agents. It is utilized in agrochemical production for creating herbicides and pesticides due to its bioactivity-enhancing trifluoromethyl group. Researchers also employ it in material science for developing liquid crystals and functional polymers.

Safety and Hazards

GHS Hazard Statements

• H301 (85.4%): Toxic if swallowed [Danger Acute toxicity, oral]
• H302 (14.6%): Harmful if swallowed [Warning Acute toxicity, oral]
• H311 (85.4%): Toxic in contact with skin [Danger Acute toxicity, dermal]
• H312 (10.4%): Harmful in contact with skin [Warning Acute toxicity, dermal]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (97.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H332 (95.8%): Harmful if inhaled [Warning Acute toxicity, inhalation]
• H335 (87.5%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
• H400 (87.5%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

Precautionary Statements

• P261, P262, P264, P264+P265, P270, P271, P273, P280, P301+P316, P301+P317, P302+P352, P304+P340, P305+P351+P338, P316, P317, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P391, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 3 (85.4%)
• Acute Tox. 4 (14.6%)
• Acute Tox. 3 (85.4%)
• Acute Tox. 4 (10.4%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (97.9%)
• Acute Tox. 4 (95.8%)
• STOT SE 3 (87.5%)
• Aquatic Acute 1 (87.5%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.