Description
4,4′-Difluorodiphenyl sulfone (CAS No. 383-29-9) is a high-purity sulfone derivative with the molecular formula C12H8F2O2S. This aromatic compound, also known as 1-fluoro-4-(4-fluorophenyl)sulfonylbenzene (IUPAC), features a sulfonyl bridge connecting two fluorinated phenyl rings, offering exceptional thermal stability and chemical resistance. Ideal for advanced polymer synthesis, pharmaceutical intermediates, and specialty chemical applications, this white crystalline solid is rigorously tested for purity (typically ≥98%) via HPLC and GC analysis. Packaged under inert conditions to ensure stability, it is a critical building block for high-performance polyethersulfones (PES) and other engineering plastics. Available in research (1g-100g) and bulk (1kg+) quantities with customizable packaging options.
Properties
- CAS Number: 383-29-9
- Complexity: 306
- IUPAC Name: 1-fluoro-4-(4-fluorophenyl)sulfonyl-benzene
- InChI: InChI=1S/C12H8F2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H
- InChI Key: PLVUIVUKKJTSDM-UHFFFAOYSA-N
- Exact Mass: 254.02130699
- Molecular Formula: C12H8F2O2S
- Molecular Weight: 254.25
- SMILES: C1=CC(=CC=C1F)S(=O)(=O)C2=CC=C(C=C2)F
- Topological: 42.5
- Monoisotopic Mass: 254.02130699
- Physical Description: White, odorless, crystalline powder;
- Synonyms: 383-29-9, 4,4′-Difluorodiphenyl sulfone, Bis(4-fluorophenyl)sulfone, Benzene, 1,1′-sulfonylbis[4-fluoro-, 4-Fluorophenylsulfone, Bis(p-fluorophenyl) sulfone, Sulfone, bis(p-fluorophenyl), 1,1′-sulfonylbis(4-fluorobenzene), Bis(p-fluorophenyl)sulphone, NSC 87584, Benzene, 1,1′-sulfonylbis(4-fluoro-, NSC 683542, EINECS 206-847-4, DTXSID2059934, 1,1′-Sulfonylbis[4-fluorobenzene], 4Fluorophenylsulfone, Bis(4fluorophenyl)sulfone, Bis(pfluorophenyl)sulphone, Bis(pfluorophenyl) sulfone, Sulfone, bis(pfluorophenyl), DTXCID6039471, Benzene, 1,1’sulfonylbis(4fluoro, Sulfone, bis(pfluorophenyl) (8CI), Sulfone, bis(p-fluorophenyl) (8CI), 206-847-4, inchi=1/c12h8f2o2s/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8, 4-Fluorophenyl sulfone, 4,4′-Sulfonylbis(fluorobenzene), Bis(4-fluorophenyl) sulfone, 1-fluoro-4-(4-fluorophenyl)sulfonylbenzene, MFCD00000350, 4,4′-Difluorodiphenylsulfone, bis(p-fluorophenyl)sulfone, KW93VS9RT8, 4-fluorophenyl sulphone, 1-fluoro-4-(4-fluorophenyl)sulfonyl-benzene, NSC87584, NSC-87584, NSC683542, NSC-683542, C12H8F2O2S, 4-fluoro-1-[(4-fluorophenyl)sulfonyl]benzene, bis(4-fluorophenyl)sulphone, 1-fluoro-4-(4-fluorobenzenesulfonyl)benzene, Enamine_005215, p,p’-Difluordiphenylsulfon, UNII-KW93VS9RT8, Cambridge id 5192838, Oprea1_616663, SCHEMBL79787, bis(4-fluorophenyl) sulphone, Bis-(4-fluorophenyl) sulfone, Sulphone, bis(p-fluorophenyl), Bis-(4-fluorophenyl) sulphone, SCHEMBL2121770, Sulfone, bis(4-fluorophenyl)-, 4,4a(2)-Difluorodiphenyl sulfone, Benzene,1′-sulfonylbis[4-fluoro-, HMS1408N01, Bis(4-fluorophenyl) sulfone, 99%, 1,1′-Sulphonylbis[4-fluorobenzene], BBL023351, SBB080519, STL355979, AKOS001064866, AC-4575, CS-W010189, DS-1286, PS-7428, Benzene, 1,1′-sulphonylbis(4-fluoro-, IDI1_007802, NCGC00329318-01, SY038237, DB-049267, D0537, NS00042222, ST50164322, ST50997552, O11120, 1-Fluoro-4-[(4-fluorophenyl)sulfonyl]benzene #, AB01222579-03, Z56888626, 4,4 inverted exclamation mark -Difluorodiphenyl Sulfone, Bis(p-fluorophenyl) sulfone;4,4′-Difluorodiphenyl sulfone
Application
4,4′-Difluorodiphenyl sulfone serves as a key monomer in synthesizing polyethersulfone (PES) polymers, widely used in high-temperature membranes and medical devices due to its thermal stability. It acts as a precursor in pharmaceutical intermediates, particularly for fluorine-containing bioactive molecules. The compound is also employed in liquid crystal polymers (LCPs) and as a crosslinking agent in specialty resins for aerospace applications.
Safety and Hazards
GHS Hazard Statements
- H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]
- H312 (50%): Harmful in contact with skin [Warning Acute toxicity, dermal]
- H315 (75%): Causes skin irritation [Warning Skin corrosion/irritation]
- H319 (75%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
- H332 (50%): Harmful if inhaled [Warning Acute toxicity, inhalation]
- H335 (75%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statements
- P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Hazard Classes and Categories
- Acute Tox. 4 (50%)
- Acute Tox. 4 (50%)
- Skin Irrit. 2 (75%)
- Eye Irrit. 2 (75%)
- Acute Tox. 4 (50%)
- STOT SE 3 (75%)
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