Description

Hexafluoroamylene glycol (CAS No. 376-90-9), also known as 2,2,3,3,4,4-hexafluoropentane-1,5-diol, is a high-purity fluorinated diol with the molecular formula C₅H₆F₆O₂. This specialty chemical features a unique hexafluorinated carbon backbone, offering exceptional hydrophobicity, chemical stability, and resistance to degradation under harsh conditions. Its bifunctional hydroxyl groups make it a versatile building block for synthesizing advanced fluorinated polymers, surfactants, and coatings. Ideal for research and industrial applications, our product is rigorously tested to ensure ≥98% purity (GC) and is supplied in sealed containers to maintain integrity. Suitable for use in pharmaceuticals, agrochemicals, and material science, Hexafluoroamylene glycol is a critical reagent for scientists developing next-generation fluorinated materials.

Properties

• CAS Number: 376-90-9
• Complexity: 162
• IUPAC Name: 2,2,3,3,4,4-hexafluoropentane-1,5-diol
• InChI: InChI=1S/C5H6F6O2/c6-3(7,1-12)5(10,11)4(8,9)2-13/h12-13H,1-2H2
• InChI Key: IELVMUPSWDZWSD-UHFFFAOYSA-N
• Exact Mass: 212.02719840
• Molecular Formula: C5H6F6O2
• Molecular Weight: 212.09
• SMILES: C(C(C(C(CO)(F)F)(F)F)(F)F)O
• Topological: 40.5
• Monoisotopic Mass: 212.02719840
• Synonyms: 2,2,3,3,4,4-Hexafluoro-1,5-pentanediol, 376-90-9, 2,2,3,3,4,4-Hexafluoropentane-1,5-diol, Hexafluoroamylene glycol, 1,5-Pentanediol, 2,2,3,3,4,4-hexafluoro-, 2,2,3,3,4,4-Hexafluoropentanediol, EINECS 206-819-1, F2KZY84Y8G, NSC 29196, NSC-29196, DTXSID3059927, IELVMUPSWDZWSD-UHFFFAOYSA-, DTXCID9039369, inchi=1/c5h6f6o2/c6-3(7,1-12)5(10,11)4(8,9)2-13/h12-13h,1-2h2, Hexafluoro-1,5-pentanediol, 1,5-Dihydroxy-2,2,3,3,4,4-hexafluoropentane, 2,2,3,3,4,4-Hexafluoropentan-1,5-diol, MFCD00042434, NSC29196, UNII-F2KZY84Y8G, SCHEMBL851143, SCHEMBL1535878, 2,3,3,4,4-Hexafluoropentanediol, SBB094592, 1, 2,2,3,3,4,4-hexafluoro-, AKOS015852931, AT23339, FH60454, 1h,1h,5h,5h-perfluoro-1,5-pentanediol, BS-43804, SY057144, 2,3,3,4,4-Hexafluoro-1,5-pentanediol, DB-049174, CS-0217834, H0746, NS00019037, 2,2,3,3,4,4-hexafluoro-pentane-1,5-diol, EN300-87257, 2,2,3,3,4,4-Hexafluoro-1,5-pentanediol, 98%, 1,5-Dihydroxy-2,2,3,3,4,4-hexafluoropentane;FPF-1

Application

Hexafluoroamylene glycol is widely used as a key intermediate in the synthesis of fluorinated polymers and elastomers, enhancing their thermal and chemical resistance. In pharmaceutical research, it serves as a precursor for prodrugs and bioactive molecules due to its ability to modulate lipophilicity. The compound is also employed in the development of specialized surfactants and coatings, where its fluorinated structure imparts water-repellent and anti-fouling properties.

Safety and Hazards

GHS Hazard Statements

• H302 (97.9%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (17%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (17%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (14.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (97.9%)
• Skin Irrit. 2 (17%)
• Eye Irrit. 2A (17%)
• STOT SE 3 (14.9%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.