Get FREE SHIPPING when you spend $99 or more | ATOMFAIR

Awaiting product image

Atomfair 2-Bromo-3-fluoro-6-methylpyridine C6H5BrFN CAS 374633-36-0

2-Bromo-3-fluoro-6-methylpyridine (CAS No. 374633-36-0) is a high-purity halogenated pyridine derivative with the molecular formula C6H5BrFN. This compound is a versatile building block in pharmaceutical and agrochemical synthesis, offering selective reactivity due to its bromo and fluoro substituents on the pyridine ring. Its crystalline form and well-defined structure (IUPAC name: 2-bromo-3-fluoro-6-methylpyridine) ensure consistent performance in cross-coupling reactions, nucleophilic substitutions, and metal-catalyzed transformations. Packaged under inert conditions to maintain stability, this reagent is ideal for researchers requiring precise intermediates in drug discovery and material science applications. Available in quantities from milligrams to kilograms, with optional certificates of analysis (CoA) upon request.

Category:

Description

2-Bromo-3-fluoro-6-methylpyridine (CAS No. 374633-36-0) is a high-purity halogenated pyridine derivative with the molecular formula C6H5BrFN. This compound is a versatile building block in pharmaceutical and agrochemical synthesis, offering selective reactivity due to its bromo and fluoro substituents on the pyridine ring. Its crystalline form and well-defined structure (IUPAC name: 2-bromo-3-fluoro-6-methylpyridine) ensure consistent performance in cross-coupling reactions, nucleophilic substitutions, and metal-catalyzed transformations. Packaged under inert conditions to maintain stability, this reagent is ideal for researchers requiring precise intermediates in drug discovery and material science applications. Available in quantities from milligrams to kilograms, with optional certificates of analysis (CoA) upon request.

Properties

  • CAS Number: 374633-36-0
  • Complexity: 99.1
  • IUPAC Name: 2-bromo-3-fluoro-6-methyl-pyridine
  • InChI: InChI=1S/C6H5BrFN/c1-4-2-3-5(8)6(7)9-4/h2-3H,1H3
  • InChI Key: KKVUMKHUMBXLMH-UHFFFAOYSA-N
  • Exact Mass: 188.95894
  • Molecular Formula: C6H5BrFN
  • Molecular Weight: 190.01
  • SMILES: CC1=NC(=C(C=C1)F)Br
  • Topological: 12.9
  • Monoisotopic Mass: 188.95894
  • Synonyms: 2-Bromo-3-fluoro-6-methylpyridine, 374633-36-0, DTXSID00647479, DTXCID00598230, 696-217-9, 2-Bromo-3-fluoro-6-picoline, 2-bromo-3-fluoro-6-methyl-pyridine, MFCD03095061, SCHEMBL319343, KKVUMKHUMBXLMH-UHFFFAOYSA-N, BCP06450, AKOS005762871, AC-1706, CS-W019922, PS-8393, SB18589, SY019783, EN300-98132, 2-Bromo-3-fluoro-6-methylpyridine, AldrichCPR

Application

2-Bromo-3-fluoro-6-methylpyridine serves as a key intermediate in the synthesis of biologically active compounds, particularly in the development of fluorinated pharmaceuticals and agrochemicals. Its reactive halogen sites enable efficient Suzuki-Miyaura and Buchwald-Hartwig coupling reactions for constructing complex heterocycles. Researchers also utilize it in the preparation of fluorinated ligands for catalysis and functional materials.

Safety and Hazards

GHS Hazard Statements

  • H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
  • H312 (50%): Harmful in contact with skin [Warning Acute toxicity, dermal]
  • H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (50%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H332 (50%): Harmful if inhaled [Warning Acute toxicity, inhalation]
  • H335 (50%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Acute Tox. 4 (100%)
  • Acute Tox. 4 (50%)
  • Skin Irrit. 2 (50%)
  • Eye Irrit. 2 (50%)
  • Acute Tox. 4 (50%)
  • STOT SE 3 (50%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.

Related products