Description
2-Bromo-5-methylpyridine (CAS No. 3510-66-5) is a high-purity halogenated pyridine derivative with the molecular formula C6H6BrN. This organic compound is widely used as a key intermediate in pharmaceutical synthesis, agrochemical development, and materials science research. The bromine substitution at the 2-position and methyl group at the 5-position make it a versatile building block for cross-coupling reactions, including Suzuki, Negishi, and Stille couplings.
Our product is supplied as a clear to pale yellow liquid with a purity of ≥98%, ensuring optimal reactivity for demanding synthetic applications. It is rigorously tested via GC/MS, NMR, and HPLC to meet the highest industry standards. Proper storage under inert gas (e.g., argon) at 2-8°C is recommended to maintain stability.
Key Features:
- Molecular Weight: 172.02 g/mol
- Boiling Point: ~205-207°C
- Density: 1.47 g/cm3
- Refractive Index: nD20 1.556
- Hazard Codes: Xi (Irritant)
Properties
- CAS Number: 3510-66-5
- Complexity: 74.9
- IUPAC Name: 2-bromo-5-methyl-pyridine
- InChI: InChI=1S/C6H6BrN/c1-5-2-3-6(7)8-4-5/h2-4H,1H3
- InChI Key: YWNJQQNBJQUKME-UHFFFAOYSA-N
- Exact Mass: 170.96836
- Molecular Formula: C6H6BrN
- Molecular Weight: 172.02
- SMILES: CC1=CN=C(C=C1)Br
- Topological: 12.9
- Monoisotopic Mass: 170.96836
- Synonyms: 2-Bromo-5-methylpyridine, 3510-66-5, Pyridine, 2-bromo-5-methyl-, DTXSID50188600, DTXCID70111091, 609-062-9, inchi=1/c6h6brn/c1-5-2-3-6(7)8-4-5/h2-4h,1h, ywnjqqnbjqukme-uhfffaoysa-n, 2-Bromo-5-picoline, 6-Bromo-3-picoline, 2-bromo-5-methyl-pyridine, MFCD00209553, 2-Bromo-5-Methyl Pyridine, 5-METHYL-2-BROMOPYRIDINE, 2-bromo5-methylpyridine, bromo-5-methyl pyridine, 2-bromo-5-methylpyridin, 2-bromo-5methyl-pyridine, 6-bromo-3-methylpyridine, 2-bromo -5-methylpyridine, 2-bromo-5 methyl-pyridine, 2-Bromo-5-methylpyridine (2-Bromo-5-picoline), 2-bromanyl-5-methyl-pyridine, SCHEMBL189127, SCHEMBL693094, SCHEMBL3604396, 2-Bromo-5-methylpyridine, 98%, BCP22147, SBB054301, AKOS005206804, AC-2426, CS-W007353, FG-0495, HY-W007353, PB17145, SY001056, B2113, NS00029773, ST50826947, EN300-73429, A822569, doi:10.14272/YWNJQQNBJQUKME-UHFFFAOYSA-N.1, Z415645054
2-Bromo-5-methylpyridine serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and antiviral agents. It is employed in palladium-catalyzed cross-coupling reactions to construct complex heterocyclic scaffolds. Researchers also utilize this compound in material science for developing organic semiconductors and liquid crystal displays (LCDs). Its reactivity makes it valuable for introducing pyridine motifs in agrochemicals like herbicides and fungicides.
Safety and Hazards
GHS Hazard Statements
- H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
- H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
- H335 (97.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statements
- P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Hazard Classes and Categories
- Skin Irrit. 2 (100%)
- Eye Irrit. 2 (100%)
- STOT SE 3 (97.9%)
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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.


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