Description

1-Bromo-4-fluoronaphthalene (CAS No. 341-41-3) is a high-purity halogenated naphthalene derivative with the molecular formula C₁₀H₆BrF. This aromatic compound is characterized by its bromine and fluorine substituents at the 1- and 4-positions of the naphthalene ring, respectively, making it a valuable intermediate in organic synthesis and materials science. With a molecular weight of 225.06 g/mol, it is a crystalline solid at room temperature, offering excellent stability under standard laboratory conditions. Ideal for researchers in pharmaceuticals, agrochemicals, and advanced material development, our product is rigorously tested to ensure ≥98% purity (GC) and is supplied in sealed, light-resistant containers to maintain integrity. Suitable for Suzuki couplings, nucleophilic substitutions, and as a building block for liquid crystals or OLED materials.

Properties

• CAS Number: 341-41-3
• Complexity: 160
• IUPAC Name: 1-bromo-4-fluoro-naphthalene
• InChI: InChI=1S/C10H6BrF/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6H
• InChI Key: VAUJZKBFENPOCH-UHFFFAOYSA-N
• Exact Mass: 223.96369
• Molecular Formula: C10H6BrF
• Molecular Weight: 225.06
• SMILES: C1=CC=C2C(=C1)C(=CC=C2Br)F
• Monoisotopic Mass: 223.96369
• Synonyms: 1-Bromo-4-fluoronaphthalene, 341-41-3, 1-fluoro-4-bromonaphthalene, EINECS 206-434-9, Naphthalene, 1-bromo-4-fluoro-, DTXSID30187691, DTXCID90110182, 206-434-9, vaujzkbfenpoch-uhfffaoysa-n, 4-bromo-1-fluoronaphthalene, MFCD00051473, 1-Fluoro-4-bromonaphthalene; 4-Fluoro-1-naphthyl Bromide;, 1-bromo-4-fluoro-naphthalene, 1-bromo 4-fluoronaphthalene, 1-bromo-4-fluoro naphthalene, SCHEMBL155660, 1-Bromo-4-fluoronaphthalene, 97%, SBB096776, AKOS003349450, CS-W013050, PS-7786, SY021554, DB-019082, B3797, NS00041873, ST45025049, EN300-352280

Application

1-Bromo-4-fluoronaphthalene is widely used as a key precursor in cross-coupling reactions (e.g., Suzuki-Miyaura) to synthesize biaryl compounds for pharmaceutical and material applications. Its halogenated structure enables facile functionalization in the development of liquid crystals, organic semiconductors, and fluorescent dyes. Researchers also employ it as a model substrate in mechanistic studies of aromatic substitution reactions.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (95.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (95.7%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.