Description

4-(Trimethoxysilyl)aniline (CAS No. 33976-43-1) is a highly versatile organosilane coupling agent with the molecular formula C₉H₁₅NO₃Si. This compound features both an amine (-NH₂) functional group and hydrolyzable trimethoxysilyl groups, making it an excellent intermediate for surface modification, adhesion promotion, and polymer crosslinking. Ideal for researchers and scientists working in materials science, nanotechnology, and coatings, this product enhances interfacial bonding between organic polymers and inorganic substrates such as glass, metals, and silica. Its high purity and stability ensure reliable performance in applications requiring covalent surface functionalization. Packaged under inert conditions to maintain integrity, it is suitable for use in controlled laboratory and industrial environments.

Properties

• CAS Number: 33976-43-1
• Complexity: 159
• IUPAC Name: 4-trimethoxysilylaniline
• InChI: InChI=1S/C9H15NO3Si/c1-11-14(12-2,13-3)9-6-4-8(10)5-7-9/h4-7H,10H2,1-3H3
• InChI Key: CNODSORTHKVDEM-UHFFFAOYSA-N
• Exact Mass: 213.08211987
• Molecular Formula: C9H15NO3Si
• Molecular Weight: 213.31
• SMILES: CO[Si](C1=CC=C(C=C1)N)(OC)OC
• Topological: 53.7
• Monoisotopic Mass: 213.08211987
• Synonyms: 4-(Trimethoxysilyl)aniline, 33976-43-1, EINECS 251-772-2, DTXSID30955554, DTXCID001383544, 251-772-2, aminophenyltrimethoxysilane, p-aminophenyltrimethoxysilane, 4-trimethoxysilylaniline, Benzenamine, 4-(trimethoxysilyl)-, MFCD00054700, SCHEMBL110157, CNODSORTHKVDEM-UHFFFAOYSA-N, IBA97643, BBL103038, STL556847, AKOS008901163, DB-112918, NS00054853, G86066, Aminophenyltrimethoxysilane (contains all isomers)

4-(Trimethoxysilyl)aniline is widely used as a silane coupling agent to improve adhesion between organic resins and inorganic surfaces in composites, adhesives, and coatings. It serves as a key precursor for synthesizing functionalized surfaces in biosensors and diagnostic devices due to its amine reactivity. Researchers also employ it in sol-gel processes to create hybrid organic-inorganic materials with tailored properties for advanced material applications.

Safety and Hazards

GHS Hazard Statements

• H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
• H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]
• H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.