Description
Aspartic acid, 2-methyl- (CAS No. 3227-17-6) is a high-purity, non-proteinogenic amino acid derivative widely utilized in biochemical research and pharmaceutical applications. This compound, with the molecular formula C5H9NO4, is a chiral analog of L-aspartic acid featuring a methyl substitution at the alpha position, enhancing its utility in stereospecific studies. It is available in >98% purity (HPLC) and is supplied as a white crystalline powder, ensuring consistent performance in enzymatic assays, peptide synthesis, and neurotransmitter research. Ideal for neuroscientists and chemists, this product is rigorously tested for endotoxins, heavy metals, and residual solvents to meet stringent laboratory standards. Store at 2-8°C in a tightly sealed container to maintain stability.
Properties
- CAS Number: 3227-17-6
- Complexity: 167
- IUPAC Name: (2S)-2-amino-2-methyl-butanedioic acid
- InChI: InChI=1S/C5H9NO4/c1-5(6,4(9)10)2-3(7)8/h2,6H2,1H3,(H,7,8)(H,9,10)/t5-/m0/s1
- InChI Key: CWAYDJFPMMUKOI-YFKPBYRVSA-N
- Exact Mass: 147.05315777
- Molecular Formula: C5H9NO4
- Molecular Weight: 147.13
- SMILES: C[C@](CC(=O)O)(C(=O)O)N
- Topological: 101
- Monoisotopic Mass: 147.05315777
- Synonyms: 3227-17-6, Aspartic acid, 2-methyl-, 2-Methyl-L-Aspartic Acid, (2S)-2-amino-2-methylbutanedioic acid, (S)-(+)-2-AMINO-2-METHYLBUTANEDIOIC ACID, (S)-2-amino-2-methylsuccinic acid, (2S)-2-AMINO-2-METHYLSUCCINIC ACID, l-alpha-methylaspartic acid, alpha-Me-Asp-OH, H-ALPHA-ME-L-ASP-OH, NSC-14963, beta-Me-Asp-OH, A-METHYL-L-ASP, L-2-Methylaspartic acid, (S)-2-Methylaspartic acid, alpha-methyl-l-aspartic acid, D4E8N3KD5V, L-Aspartic acid, 2-methyl-, SCHEMBL162455, Aspartic acid, 2-methyl-, L-, (S)-ALPHA-METHYLASPARTIC ACID, AKOS006271876, AB03942, AT34714, AS-82114, Q27449941, 0A0
Aspartic acid, 2-methyl- is primarily used as a competitive inhibitor in glutamate receptor studies, particularly for NMDA and AMPA receptors. It serves as a key intermediate in the synthesis of modified peptides and enzyme substrates due to its stereochemical properties. Researchers also employ it in metabolic pathway analysis and as a chiral building block for pharmaceuticals targeting neurological disorders.
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