Description
2,3,5-Tribromothiophene (CAS No. 3141-24-0) is a high-purity brominated thiophene derivative with the molecular formula C4HBr3S. This compound is widely utilized in organic synthesis, pharmaceutical research, and material science due to its reactive bromine substituents, which make it a valuable intermediate for cross-coupling reactions, polymerization, and functionalization of heterocyclic frameworks. With a purity of ≥96%, our product is rigorously tested via GC/MS, NMR, and HPLC to ensure consistency and reliability for sensitive applications. Suitable for use in controlled environments, it is packaged under inert conditions to maintain stability. Available in quantities from milligrams to kilograms, this reagent is ideal for researchers seeking precision in brominated heterocycle chemistry.
Properties
- CAS Number: 3141-24-0
- Complexity: 87.4
- IUPAC Name: 2,3,5-tribromothiophene
- InChI: InChI=1S/C4HBr3S/c5-2-1-3(6)8-4(2)7/h1H
- InChI Key: SKDNDSLDRLEELJ-UHFFFAOYSA-N
- Exact Mass: 319.73286
- Molecular Formula: C4HBr3S
- Molecular Weight: 320.83
- SMILES: C1=C(SC(=C1Br)Br)Br
- Topological: 28.2
- Monoisotopic Mass: 317.73491
- Synonyms: 2,3,5-Tribromothiophene, 3141-24-0, Thiophene, 2,3,5-tribromo-, EINECS 221-544-7, NSC 263503, AI3-62838, DTXSID8062862, DTXCID3038357, 221-544-7, MFCD00014521, NSC-263503, C4HBr3S, NSC263503, 2,5-Tribromothiophene, HX5MEU6VFT, Thiophene,3,5-tribromo-, 2,3,5-Triibromothiophene, 2,3,5-tribromo thiophene, 2,3,5-Tribromo-thiophene, SCHEMBL350437, SCHEMBL917122, 2,3,5-Tribromothiophene, 96%, AKOS005259584, AC-4902, CS-W012003, SB66352, AS-13417, SY015567, DB-048029, NS00029085, ST50408549, T0956, EN300-83782, InChI=1/C4HBr3S/c5-2-1-3(6)8-4(2)7/h1
2,3,5-Tribromothiophene serves as a key intermediate in the synthesis of advanced organic electronic materials, including conductive polymers and liquid crystals. Its bromine groups enable efficient Suzuki-Miyaura and Stille cross-coupling reactions for constructing complex thiophene-based architectures. Researchers also employ it in pharmaceutical development for modifying bioactive molecules. Additionally, it finds use in agrochemical research and as a flame retardant precursor.
Safety and Hazards
GHS Hazard Statements
- H302 (97.9%): Harmful if swallowed [Warning Acute toxicity, oral]
- H312 (97.9%): Harmful in contact with skin [Warning Acute toxicity, dermal]
- H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
- H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
- H332 (95.8%): Harmful if inhaled [Warning Acute toxicity, inhalation]
- H335 (91.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statements
- P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Hazard Classes and Categories
- Acute Tox. 4 (97.9%)
- Acute Tox. 4 (97.9%)
- Skin Irrit. 2 (100%)
- Eye Irrit. 2 (100%)
- Acute Tox. 4 (95.8%)
- STOT SE 3 (91.7%)
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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.


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