Description

Arabinofuranosyluracil (Ara-U) is a nucleoside analog derived from uracil and arabinose, widely recognized for its role in biochemical and pharmaceutical research. With the molecular formula C₉H₁₂N₂O₆ and CAS number 3083-77-0, this high-purity compound is essential for studying antiviral mechanisms, nucleoside metabolism, and potential therapeutic applications. Ara-U exhibits structural similarity to naturally occurring nucleosides, making it a valuable tool for probing enzyme specificity, DNA/RNA synthesis inhibition, and antimetabolite activity.

Our Ara-U is rigorously tested for purity and stability, ensuring reliable performance in in vitro and in vivo studies. It is supplied as a white to off-white crystalline powder, soluble in water and DMSO, with detailed analytical data (HPLC, NMR) available upon request. Ideal for researchers investigating antiviral agents (e.g., herpesvirus), cancer therapeutics, or nucleotide biochemistry.

Key Features:

• ≥98% purity (HPLC-grade)
• Stable under recommended storage conditions (-20°C)
• Compatible with enzymatic assays and cell culture studies
• Supported by comprehensive MSDS and technical documentation

Properties

• CAS Number: 3083-77-0
• Complexity: 370
• IUPAC Name: 1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione
• InChI: InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7+,8-/m1/s1
• InChI Key: DRTQHJPVMGBUCF-CCXZUQQUSA-N
• Exact Mass: 244.06953611
• Molecular Formula: C9H12N2O6
• Molecular Weight: 244.20
• SMILES: C1=CN(C(=O)NC1=O)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O
• Topological: 119
• Monoisotopic Mass: 244.06953611
• Synonyms: 3083-77-0, ARABINOFURANOSYLURACIL, Arauridine, 1-beta-D-Arabinofuranosyluracil, Uracil arabinoside, Ara-U, Spongouridin, Uridine arabinoside, Uracil-beta-D-arabinofuranoside, Arabinosyluracil, 1beta-D-Arabinofuranosyluracil, 1-beta-D-Arabinofurnosyluracil, ZK0WMW5NQF, 2,4(1H,3H)-Pyrimidinedione, 1-beta-D-arabinofuranosyl-, EINECS 221-386-9, BRN 0028749, Uracil, 1-beta-D-arabinofuranosyl-, DTXSID80184832, 5-24-06-00136 (Beilstein Handbook Reference), URACIL ARABINOSIDE [USP-RS], NSC-68928, Uracil, 1-.beta.-D-arabinofuranosyl-, 2,4(1H,3H)-Pyrimidinedione, 1-.beta.-D-arabinofuranosyl-, 1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione, Sponguridine, 1-.BETA.-D-ARABINOFURANOSYL-2,4(1H,3H)-PYRIMIDINEDIONE, URACIL ARABINOSIDE (USP-RS), Arabinoside, Uracil, Ara U, Uracil Arabinofuranoside, Arabinofuranoside, Uracil, 1 beta D Arabinofuranosyl Uracil, 1-beta-D-Arabinofuranosyl Uracil, 1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)pyrimidine-2,4-dione, Uracil, 1-beta-D-Arabinofuranosyl, DTXCID20107323, Uracil, 1-beta-D-arabinofuranosyl-(VAN), Uracil, 1-beta-D-arabinofuranosyl-(VAN) (8CI), 1-BETA-D-ARABINOFURANOSYL-2,4(1H,3H)-PYRIMIDINEDIONE, 1-(3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)pyrimidine-2,4-dione, 1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione, Spongouridine, Uracil 1-|A-D-arabinofuranoside, MFCD00065998, CHEBI:68346, 1-b-D-Arabinofuranosyluracil, Spongouridine (VAN), 1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione, 1-beta-D-Arabinofuranosylpyrimidine-2,4(1H,3H)-dione (Uracil Arabinoside), NSC 68928, 1-beta-D-Arabinofuranosyl-(1H,3H)-pyrimidine-2,4-dione, UNII-ZK0WMW5NQF, Uracil, 1-beta-D-arabinofuranosyl- (VAN), 1-eta–rabinofuranosyluracl, 1-?-D-Arabinofuranosyluracil, SCHEMBL359587, Uracil 1–D-arabinofuranoside, 1-(b-D-Arabinofuranosyl)uracil, CHEMBL1092065, HY-N6652R, Uracil 1-??-D-arabinofuranoside, DRTQHJPVMGBUCF-CCXZUQQUSA-N, uracil-1-beta-D-arabinofuranoside, 1-(beta-D-arabinofuranosyl)uracil, BCP29295, HY-N6652, HG1013, s4807, Uracil 1- beta -D-arabinofuranoside, AKOS015969693, CCG-266899, NA05962, 1-| cent-D-ARABINOFURANOSYLURACIL, BP-43549, DS-14592, 1-beta-D-Arabinofuranosyluracil (Standard), CS-0083204, NS00076410, SW220050-1, Ara-U;Arauridine;Uracil 1-b-D-arabinofuranoside, 1-(beta-D-arabinofuranosyl)-pyrimidin-2,4(3H)-dione, BRD-K32566431-001-01-4, Q27136843, 2,4(1H,3H)-Pyrimidinedione, 1-|A-D-arabinofuranosyl-, Uracil 1-beta-D-arabinofuranoside, lymphoma antiproliferative, Uracil arabinoside, European Pharmacopoeia (EP) Reference Standard, Uracil arabinoside, United States Pharmacopeia (USP) Reference Standard

Arabinofuranosyluracil serves as a critical reference standard in virology research, particularly for studying herpes simplex virus (HSV) inhibition mechanisms. It acts as a competitive substrate for viral thymidine kinase, enabling targeted disruption of viral DNA synthesis. In oncology, Ara-U has demonstrated antiproliferative effects in lymphoma studies by interfering with nucleotide salvage pathways. Researchers also utilize this compound to investigate nucleoside transport systems and metabolic resistance in genetically modified cell lines.

Safety and Hazards

GHS Hazard Statements

• H361 (50%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

Precautionary Statements

• P203, P280, P318, P405, and P501

Hazard Classes and Categories

• Repr. 2 (50%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.