Description

2,3,5,6-Tetrafluoropyridine (CAS No. 2875-18-5) is a highly fluorinated pyridine derivative with the molecular formula C₅HF₄N. This specialized chemical compound is characterized by its unique tetrafluoro-substituted aromatic ring structure, making it a valuable intermediate in organic synthesis and materials science. With a purity grade suitable for research and industrial applications, our product is rigorously tested to ensure consistency and reliability. It is commonly employed in the synthesis of pharmaceuticals, agrochemicals, and advanced materials due to its electron-withdrawing properties and reactivity. Available in various quantities, this compound is packaged under inert conditions to maintain stability and shelf life.

Properties

• CAS Number: 2875-18-5
• Complexity: 108
• IUPAC Name: 2,3,5,6-tetrafluoropyridine
• InChI: InChI=1S/C5HF4N/c6-2-1-3(7)5(9)10-4(2)8/h1H
• InChI Key: HWIPMBCMGVXOKN-UHFFFAOYSA-N
• Exact Mass: 151.00451168
• Molecular Formula: C5HF4N
• Molecular Weight: 151.06
• SMILES: C1=C(C(=NC(=C1F)F)F)F
• Topological: 12.9
• Monoisotopic Mass: 151.00451168
• Synonyms: 2,3,5,6-Tetrafluoropyridine, Pyridine, 2,3,5,6-tetrafluoro-, HWIPMBCMGVXOKN-UHFFFAOYSA-, DTXSID40182930, DTXCID80105421, 622-979-9, hwipmbcmgvxokn-uhfffaoysa-n, inchi=1/c5hf4n/c6-2-1-3(7)5(9)10-4(2)8/h1h, 2875-18-5, MFCD00011734, 2,3,5,6-Tetrafluoro-pyridine, SCHEMBL846319, SCHEMBL943691, BBL100036, FD2051, SBB086751, STL185614, 2,3,5,6-Tetrafluoropyridine, 95%, AKOS005063335, CS-W010966, DS-1379, SB52301, AC-24485, DB-001201, ST51040020, T1778, EN300-94220, A26160

Application

2,3,5,6-Tetrafluoropyridine is widely used as a building block in the synthesis of fluorinated heterocycles and active pharmaceutical ingredients (APIs). Its electron-deficient nature makes it a key intermediate in nucleophilic aromatic substitution reactions. Researchers also utilize this compound in the development of liquid crystals, agrochemicals, and specialty polymers. Additionally, it serves as a precursor for ligands in catalysis and as a fluorinating agent in certain reactions.

Safety and Hazards

GHS Hazard Statements

• H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]
• H302 (10%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (98%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (96%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501

Hazard Classes and Categories

• Flam. Liq. 3 (100%)
• Acute Tox. 4 (10%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (98%)
• STOT SE 3 (96%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.