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Atomfair 5-Bromo-2-chloro-3-methoxypyridine C6H5BrClNO CAS 286947-03-3

5-Bromo-2-chloro-3-methoxypyridine (CAS No. 286947-03-3) is a high-purity halogenated pyridine derivative with the molecular formula C6H5BrClNO . This compound is a versatile building block in organic synthesis, particularly in pharmaceutical and agrochemical research. Its unique structure, featuring bromo, chloro, and methoxy substituents on the pyridine ring, enables selective functionalization for the development of novel heterocyclic compounds. Supplied as a white to off-white crystalline solid with ≥95% purity (HPLC), it is ideal for cross-coupling reactions, nucleophilic substitutions, and metal-catalyzed transformations. Packaged under inert gas to ensure stability, this reagent is stored at 2-8°C to maintain optimal shelf life. Available in quantities from…

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Description

5-Bromo-2-chloro-3-methoxypyridine (CAS No. 286947-03-3) is a high-purity halogenated pyridine derivative with the molecular formula C6H5BrClNO. This compound is a versatile building block in organic synthesis, particularly in pharmaceutical and agrochemical research. Its unique structure, featuring bromo, chloro, and methoxy substituents on the pyridine ring, enables selective functionalization for the development of novel heterocyclic compounds. Supplied as a white to off-white crystalline solid with ≥95% purity (HPLC), it is ideal for cross-coupling reactions, nucleophilic substitutions, and metal-catalyzed transformations. Packaged under inert gas to ensure stability, this reagent is stored at 2-8°C to maintain optimal shelf life. Available in quantities from grams to kilograms, with custom packaging options upon request.

Properties

  • CAS Number: 286947-03-3
  • Complexity: 114
  • IUPAC Name: 5-bromo-2-chloro-3-methoxy-pyridine
  • InChI: InChI=1S/C6H5BrClNO/c1-10-5-2-4(7)3-9-6(5)8/h2-3H,1H3
  • InChI Key: GFJMOZYIDADKLJ-UHFFFAOYSA-N
  • Exact Mass: 220.92430
  • Molecular Formula: C6H5BrClNO
  • Molecular Weight: 222.47
  • SMILES: COC1=C(N=CC(=C1)Br)Cl
  • Topological: 22.1
  • Monoisotopic Mass: 220.92430
  • Synonyms: 5-bromo-2-chloro-3-methoxypyridine, 286947-03-3, DTXSID10587791, DTXCID00538555, 690-460-4, Pyridine, 5-bromo-2-chloro-3-methoxy-, MFCD08234976, 5-Bromo-2-chloro-3-methoxy-pyridine, SCHEMBL608749, GFJMOZYIDADKLJ-UHFFFAOYSA-N, AKOS015834457, AB43719, AC-3556, CS-W003476, FB42900, PS-5619, SY022257, 5-Bromo-2-chloro-3-methoxypyridine, 97%, DB-032385, EN300-136171, F1915-8912

Application

5-Bromo-2-chloro-3-methoxypyridine serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and ligands for catalysis. It is widely used in Suzuki-Miyaura and Buchwald-Hartwig coupling reactions to construct complex pyridine-based scaffolds. Researchers also employ it in the development of kinase inhibitors and antimicrobial agents due to its electron-deficient aromatic system.

Safety and Hazards

GHS Hazard Statements

  • H301 (95.1%): Toxic if swallowed [Danger Acute toxicity, oral]
  • H318 (95.1%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

Precautionary Statements

  • P264, P264+P265, P270, P280, P301+P316, P305+P354+P338, P317, P321, P330, P405, and P501

Hazard Classes and Categories

  • Acute Tox. 3 (95.1%)
  • Eye Dam. 1 (95.1%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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