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Atomfair 8-Azabicyclo(3.2.1)octane Nortropane C7H13N CAS 280-05-7

8-Azabicyclo[3.2.1]octane (CAS No. 280-05-7) is a bicyclic organic compound with the molecular formula C7H13N. This heterocyclic amine, also known as Nortropane, features a rigid bicyclic scaffold consisting of a six-membered ring fused to a five-membered ring with a bridging nitrogen atom. Its unique structure makes it a valuable intermediate in organic synthesis and pharmaceutical research, particularly in the development of tropane alkaloids and related bioactive molecules. The compound is supplied as a high-purity solid or solution, ensuring consistency for research applications. Store in a cool, dry place under inert conditions to maintain stability.

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Description

8-Azabicyclo[3.2.1]octane (CAS No. 280-05-7) is a bicyclic organic compound with the molecular formula C7H13N. This heterocyclic amine, also known as Nortropane, features a rigid bicyclic scaffold consisting of a six-membered ring fused to a five-membered ring with a bridging nitrogen atom. Its unique structure makes it a valuable intermediate in organic synthesis and pharmaceutical research, particularly in the development of tropane alkaloids and related bioactive molecules. The compound is supplied as a high-purity solid or solution, ensuring consistency for research applications. Store in a cool, dry place under inert conditions to maintain stability.

Properties

  • CAS Number: 280-05-7
  • Complexity: 80.4
  • IUPAC Name: 8-azabicyclo[3.2.1]octane
  • InChI: InChI=1S/C7H13N/c1-2-6-4-5-7(3-1)8-6/h6-8H,1-5H2
  • InChI Key: DGGKXQQCVPAUEA-UHFFFAOYSA-N
  • Exact Mass: 111.104799419
  • Molecular Formula: C7H13N
  • Molecular Weight: 111.18
  • SMILES: C1CC2CCC(C1)N2
  • Topological: 12
  • Monoisotopic Mass: 111.104799419
  • Synonyms: 8-Azabicyclo[3.2.1]octane, 280-05-7, Nortropane, 8-Azabicyclo(3.2.1)octane, Nortropan, 1.alpha.H,5.alpha.H-Nortropane, DTXSID90950681, 1alphaH,5alphaH-Nortropane, DTXCID20965228, dggkxqqcvpauea-uhfffaoysa-n, 8-aza-bicyclo[3.2.1]octane, MFCD13196389, SCHEMBL34529, SCHEMBL59510, 8-Azabicyclo[3,2,1]octane, SCHEMBL241903, SCHEMBL328894, SCHEMBL662816, SCHEMBL664010, SCHEMBL4206166, SCHEMBL4514843, SCHEMBL7059856, SCHEMBL9469727, AKOS006240286, PB15162, BS-12970, CS-0183362, EN300-89017, F2147-1257

Application

8-Azabicyclo[3.2.1]octane serves as a key precursor in the synthesis of tropane alkaloids, such as atropine and cocaine derivatives, which are studied for their pharmacological properties. Researchers utilize this compound to explore neurotransmitter interactions, particularly in the central nervous system, due to its structural similarity to bioactive tropanes. It is also employed in medicinal chemistry for the design of novel therapeutics targeting neurological disorders.

Safety and Hazards

GHS Hazard Statements

  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Skin Irrit. 2 (100%)
  • Eye Irrit. 2 (100%)
  • STOT SE 3 (100%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

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Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

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  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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