Description

(2S)-1-(2-phenylacetyl)pyrrolidine-2-carboxylic acid is a high-purity chiral compound with the molecular formula C₁₃H₁₅NO₃, widely utilized in pharmaceutical research and organic synthesis. This compound, also known as N-phenylacetyl-L-proline, features a proline backbone modified with a phenylacetyl group, making it valuable for peptide synthesis and drug development. With a CAS number of 2752-38-7, it is rigorously tested for quality (≥98% purity by HPLC) and supplied as a white to off-white crystalline powder. Its chiral (S)-configuration ensures compatibility with stereospecific reactions, while its solubility in polar organic solvents (e.g., DMSO, methanol) facilitates laboratory applications. Ideal for researchers exploring enzyme inhibitors, prodrugs, or chiral auxiliaries.

Properties

• CAS Number: 2752-38-7
• Complexity: 297
• IUPAC Name: (2S)-1-(2-phenylacetyl)pyrrolidine-2-carboxylic acid
• InChI: InChI=1S/C13H15NO3/c15-12(9-10-5-2-1-3-6-10)14-8-4-7-11(14)13(16)17/h1-3,5-6,11H,4,7-9H2,(H,16,17)/t11-/m0/s1
• InChI Key: UBQCWSGRNIOFFC-NSHDSACASA-N
• Exact Mass: 233.10519334
• Molecular Formula: C13H15NO3
• Molecular Weight: 233.26
• SMILES: C1C[C@H](N(C1)C(=O)CC2=CC=CC=C2)C(=O)O
• Topological: 57.6
• Monoisotopic Mass: 233.10519334
• Synonyms: (2S)-1-(2-phenylacetyl)pyrrolidine-2-carboxylic acid, n-phenylacetyl-l-proline, 928-037-6, 1-(phenylacetyl)-l-proline, 2752-38-7, (S)-1-(2-phenylacetyl)pyrrolidine-2-carboxylic acid, L-Proline, 1-(2-phenylacetyl)-, N-phenylacetylproline, N -phenylacetylproline, N-phenylacetyl-proline, SCHEMBL474618, CHEMBL242863, UBQCWSGRNIOFFC-NSHDSACASA-N, AKOS015840706, DB-236204, CS-0216693, F21113, EN300-12884391, (S)-1-(2-phenylacetyl)pyrrolidine-2-carboxylicacid, A1-15388

This compound serves as a key intermediate in peptide synthesis, particularly for modifying proline residues in bioactive molecules. Researchers employ it in developing enzyme inhibitors due to its structural similarity to natural substrates. Its chiral purity makes it valuable for asymmetric catalysis and stereoselective reactions in medicinal chemistry.

Safety and Hazards

GHS Hazard Statements

• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

Precautionary Statements

• P264+P265, P280, P305+P351+P338, and P337+P317

Hazard Classes and Categories

• Eye Irrit. 2 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.