Description
5-Methyl-2-phenylpyridine (CAS No. 27012-22-2) is a high-purity organic compound with the molecular formula C12H11N, widely utilized in pharmaceutical research, material science, and chemical synthesis. This heterocyclic aromatic compound features a pyridine ring substituted with a methyl group at the 5-position and a phenyl group at the 2-position, offering unique reactivity and structural versatility. Our product is rigorously tested to ensure ≥98% purity (HPLC/GC), with stringent quality control to meet the demands of advanced research applications. Available in scalable quantities (mg to kg), it is supplied in amber glass vials or sealed containers under inert gas to prevent degradation. Ideal for ligand design, catalysis, and as a building block in medicinal chemistry.
Properties
- CAS Number: 27012-22-2
- Complexity: 149
- IUPAC Name: 5-methyl-2-phenyl-pyridine
- InChI: InChI=1S/C12H11N/c1-10-7-8-12(13-9-10)11-5-3-2-4-6-11/h2-9H,1H3
- InChI Key: ZYLPQYYLLRBVOK-UHFFFAOYSA-N
- Exact Mass: 169.089149355
- Molecular Formula: C12H11N
- Molecular Weight: 169.22
- SMILES: CC1=CN=C(C=C1)C2=CC=CC=C2
- Topological: 12.9
- Monoisotopic Mass: 169.089149355
- Synonyms: 5-Methyl-2-phenylpyridine, 27012-22-2, EINECS 248-163-9, DTXSID00949783, DTXCID501377964, 248-163-9, 5-METHYL-2-PHENYL-PYRIDINE, 2-phenyl-5-methylpyridine, MFCD04114180, 64828-54-2, Pyridine, 5-methyl-2-phenyl-, 6-phenyl-3-picoline, 3-methyl-6-phenylpyridine, 2-phenyl-5-methyl pyridine, 5-methyl-2-(phenyl)pyridine, SCHEMBL404433, SCHEMBL455476, SCHEMBL714399, SCHEMBL714400, SCHEMBL3977431, SCHEMBL4611497, SCHEMBL4755791, SCHEMBL19692831, AKOS006292124, DS-7491, SY100654, DB-081307, CS-0085797, M2969, NS00050016, C74402
Application
5-Methyl-2-phenylpyridine serves as a key intermediate in the synthesis of bioactive molecules, particularly in the development of kinase inhibitors and CNS-targeting pharmaceuticals. Its structural motif is valuable in coordination chemistry for designing transition metal catalysts. Researchers also employ it as a precursor for functionalized pyridines in material science applications, such as OLEDs and conductive polymers.
Safety and Hazards
GHS Hazard Statements
- H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
- H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
Precautionary Statements
- P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364
Hazard Classes and Categories
- Skin Irrit. 2 (100%)
- Eye Irrit. 2 (100%)
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