Description

2-Bromo-1-(2,4-dichlorophenyl)ethan-1-one (CAS No. 2631-72-3) is a high-purity halogenated aromatic ketone with the molecular formula C₈H₅BrCl₂O. This compound, also known as 2,4-Dichlorophenacyl Bromide, is a versatile reagent widely used in organic synthesis and pharmaceutical research. It features a reactive bromoacetyl group adjacent to a dichlorophenyl ring, making it a valuable intermediate for nucleophilic substitution reactions, heterocyclic chemistry, and the preparation of biologically active molecules. Our product is rigorously tested for purity (>98%) and consistency, ensuring optimal performance in sensitive applications. Suitable for use in controlled laboratory environments, it is supplied in secure, chemically resistant packaging to maintain stability and shelf life.

Properties

• CAS Number: 2631-72-3
• Complexity: 174
• IUPAC Name: 2-bromo-1-(2,4-dichlorophenyl)ethanone
• InChI: InChI=1S/C8H5BrCl2O/c9-4-8(12)6-2-1-5(10)3-7(6)11/h1-3H,4H2
• InChI Key: DASJDMQCPIDJIF-UHFFFAOYSA-N
• Exact Mass: 265.89008
• Molecular Formula: C8H5BrCl2O
• Molecular Weight: 267.93
• SMILES: C1=CC(=C(C=C1Cl)Cl)C(=O)CBr
• Topological: 17.1
• Monoisotopic Mass: 265.89008
• Synonyms: 2631-72-3, 2-Bromo-1-(2,4-dichlorophenyl)ethan-1-one, 2,4-Dichlorophenacyl Bromide, EINECS 220-116-7, DTXSID80180930, DTXCID20103421, 220-116-7, 2-Bromo-2′,4′-dichloroacetophenone, 2-bromo-1-(2,4-dichlorophenyl)ethanone, 170894-53-8, Ethanone, 2-bromo-1-(2,4-dichlorophenyl)-, MFCD00053005, 2-bromo-1-(2,4-dichloro-phenyl)-ethanone, 1-(2,4-dichlorophenyl)-2-bromoethan-1-one, 2-BROMO-2,4-DICHLOROACETOPHENONE, W96MUY2Q2J, SCHEMBL641759, SCHEMBL7849105, 2-bromo-2′,4′-dichloroacetophenon, CS-M0784, CK2576, SBB003050, STL445694, 2-bromo-2′, 4′-dichloroacetophenone, AKOS000210453, FB19068, 2-bromo-2 inverted exclamation mark ,4 inverted exclamation mark -dichloroacetophenone, AC-10044, AC-33574, SY018374, 2-bromo-1-(2,4-dichlorophenyl)-ethanone, 2-Bromo-1-(2,4-dichlorophenyl)ethanone;, 2-Bromo-2′,4′-dichloroacetophenone, 97%, DB-020587, 2-bromo-1-(2,4-dichlorophenyl)-1-ethanone, D3351, NS00028086, ST50214133, EN300-130437, AN-907/25060018, F2169-0991, Ethanone,2-bromo-1-(2,4-dichlorophenyl)-,labeled withcarbon-14(9ci), 2,4-Dichlorophenacyl bromide;2,4-Dichlorophenyl bromomethyl ketone;2-Bromo-1-(2,4-dichlorophenyl)ethanone

Application

2-Bromo-1-(2,4-dichlorophenyl)ethan-1-one is a key building block in the synthesis of agrochemicals, pharmaceuticals, and specialty chemicals. It is commonly employed in the preparation of heterocyclic compounds, such as benzofurans and indoles, due to its reactive α-bromo ketone moiety. Researchers also utilize it as a photo-labile protecting group for carboxylic acids in peptide synthesis. Its electron-withdrawing dichlorophenyl group enhances reactivity in cross-coupling reactions, making it valuable for medicinal chemistry applications.

Safety and Hazards

GHS Hazard Statements

• H301 (95.2%): Toxic if swallowed [Danger Acute toxicity, oral]
• H315 (92.9%): Causes skin irritation [Warning Skin corrosion/irritation]
• H318 (95.2%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
• H335 (95.2%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 3 (95.2%)
• Skin Irrit. 2 (92.9%)
• Eye Dam. 1 (95.2%)
• STOT SE 3 (95.2%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.