Description
1H-Isoindole-1,3(2H)-dione, 4-amino- (CAS No. 2518-24-3) is a high-purity organic compound with the molecular formula C8H6N2O2. Also known as 4-aminoisoindole-1,3-dione or 3-Aminophthalimide, this heterocyclic building block is widely utilized in pharmaceutical research, agrochemical synthesis, and material science applications. The compound features an isoindole-1,3-dione core structure substituted with an amino group at the 4-position, offering versatile reactivity for further derivatization. Our product is rigorously tested for purity and consistency, making it ideal for demanding research applications. Available in various quantities with comprehensive analytical data (including HPLC, NMR, and MS) to ensure reproducibility in your experiments.
Properties
- CAS Number: 2518-24-3
- Complexity: 239
- IUPAC Name: 4-aminoisoindoline-1,3-dione
- InChI: InChI=1S/C8H6N2O2/c9-5-3-1-2-4-6(5)8(12)10-7(4)11/h1-3H,9H2,(H,10,11,12)
- InChI Key: GQBONCZDJQXPLV-UHFFFAOYSA-N
- Exact Mass: 162.042927438
- Molecular Formula: C8H6N2O2
- Molecular Weight: 162.15
- SMILES: C1=CC2=C(C(=C1)N)C(=O)NC2=O
- Topological: 72.2
- Monoisotopic Mass: 162.042927438
- Synonyms: 3-Aminophthalimide, 2518-24-3, 1H-Isoindole-1,3(2H)-dione, 4-amino-, 4-amino-2,3-dihydro-1H-isoindole-1,3-dione, DTXSID4062486, DTXCID5037236, 626-297-2, 4-Aminoisoindoline-1,3-dione, 4-aminoisoindole-1,3-dione, 4-amino-1h-isoindole-1,3(2h)-dione, MFCD00041853, F2146-0308, 3-amino-phthalamide, amino-phthalimide, 6-aminophthalimide, 3-Aminophthalimide, 97%, Oprea1_344852, SCHEMBL221618, 4-amino-1,3-isoindolinedione, ghl.PD_Mitscher_leg0.1319, SCHEMBL7222595, 4-aminobenzo[c]azoline-1,3-dione, SMSSF-0613667, BCP17751, SBB087586, STK731803, AKOS000116893, 4-amino-2H-benzo[c]azoline-1,3-dione, SY003188, TS-02155, CS-0076810, ST50824814, EN300-08155, Z56886642
Application
4-Aminoisoindole-1,3-dione serves as a key intermediate in the synthesis of pharmaceutical compounds, particularly those targeting neurological disorders. Researchers utilize this building block in the development of fluorescence probes due to its photophysical properties. The compound also finds application in polymer chemistry as a monomer for specialty polyimides with enhanced thermal stability.
Safety and Hazards
GHS Hazard Statements
- H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
- H317 (95.2%): May cause an allergic skin reaction [Warning Sensitization, Skin]
- H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
- H335 (97.6%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statements
- P261, P264, P264+P265, P271, P272, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Hazard Classes and Categories
- Skin Irrit. 2 (100%)
- Skin Sens. 1 (95.2%)
- Eye Irrit. 2 (100%)
- STOT SE 3 (97.6%)
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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.


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