Description

1,2,4-Trifluoro-5-nitrobenzene (CAS No. 2105-61-5) is a high-purity fluorinated nitrobenzene derivative with the molecular formula C₆H₂F₃NO₂. This compound is characterized by its trifluorinated aromatic ring and a nitro group at the 5-position, making it a versatile intermediate in organic synthesis and pharmaceutical research. It is supplied as a crystalline solid with exceptional purity (>98%) and is rigorously tested for consistency to meet the stringent demands of research and industrial applications. Ideal for nucleophilic aromatic substitution reactions, this compound is packaged under inert conditions to ensure stability and longevity. Suitable for use in advanced chemical synthesis, material science, and agrochemical development.

Properties

• CAS Number: 2105-61-5
• Complexity: 184
• IUPAC Name: 1,2,4-trifluoro-5-nitro-benzene
• InChI: InChI=1S/C6H2F3NO2/c7-3-1-5(9)6(10(11)12)2-4(3)8/h1-2H
• InChI Key: ROJNMGYMBLNTPK-UHFFFAOYSA-N
• Exact Mass: 177.00376279
• Molecular Formula: C6H2F3NO2
• Molecular Weight: 177.08
• SMILES: C1=C(C(=CC(=C1F)F)F)[N+](=O)[O-]
• Topological: 45.8
• Monoisotopic Mass: 177.00376279
• Synonyms: 1,2,4-Trifluoro-5-nitrobenzene, 2105-61-5, 2,4,5-Trifluoronitrobenzene, Benzene, 1,2,4-trifluoro-5-nitro-, 2,4,5-Trifluoro-1-nitrobenzene, 5-Nitro-1,2,4-trifluorobenzene, 3ZU9GWD6VV, NSC-10248, ROJNMGYMBLNTPK-UHFFFAOYSA-, DTXSID30175270, EINECS 218-281-5, NSC 10248, DTXCID3097761, 218-281-5, inchi=1/c6h2f3no2/c7-3-1-5(9)6(10(11)12)2-4(3)8/h1-2h, rojnmgymblntpk-uhfffaoysa-n, MFCD00007051, 2,4,5-trifluoro-nitrobenzene, 1,2,5-trifluoro-4-nitrobenzene, 1,2,4-trifluoro-5-nitro-benzene, NSC10248, UNII-3ZU9GWD6VV, SCHEMBL58080, SCHEMBL147740, 2,4,5-tri-fluoronitrobenzene, 2,4,5-Trifluoronitrobenzene, 99%, SBB063044, AKOS006221186, AKOS015888120, CS-W020417, AC-23673, AS-14357, DB-023816, Benzene, 1,?2,?4-?trifluoro-?5-?nitro-, NS00046067, ST50827055, T1589, EN300-99951, A25244, F0001-0004, Benzene, 1,2,4-trifluoro-5-nitro;2,4,5-Trifluoro-5-nitrobenzene;1-Nitro-2,4,5-trifluorobenzene;4-chloro-2-flurophenol

Application

1,2,4-Trifluoro-5-nitrobenzene is widely used as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals. Its electron-deficient aromatic ring makes it highly reactive in nucleophilic substitution reactions, enabling the introduction of various functional groups. Researchers also utilize it in the development of liquid crystals and specialty polymers due to its unique electronic properties. Additionally, it serves as a precursor in the preparation of fluorinated dyes and advanced materials.

Safety and Hazards

GHS Hazard Statements

• H300 (81.6%): Fatal if swallowed [Danger Acute toxicity, oral]
• H302 (10.2%): Harmful if swallowed [Warning Acute toxicity, oral]
• H312 (10.2%): Harmful in contact with skin [Warning Acute toxicity, dermal]
• H315 (95.9%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (95.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H332 (10.2%): Harmful if inhaled [Warning Acute toxicity, inhalation]
• H335 (83.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P316, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 2 (81.6%)
• Acute Tox. 4 (10.2%)
• Acute Tox. 4 (10.2%)
• Skin Irrit. 2 (95.9%)
• Eye Irrit. 2 (95.9%)
• Acute Tox. 4 (10.2%)
• STOT SE 3 (83.7%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.