Description

1,2,3,4-Tetrahydro-1-naphthoic acid (CAS No. 1914-65-4) is a high-purity organic compound with the molecular formula C₁₁H₁₂O₂. This versatile carboxylic acid derivative features a tetrahydronaphthalene backbone, making it a valuable intermediate in pharmaceutical synthesis and organic chemistry research. Our product is rigorously tested to ensure ≥98% purity by HPLC, with detailed analytical certificates available. Available in quantities from grams to kilograms, it’s supplied as a white to off-white crystalline powder with excellent batch-to-batch consistency. Proper storage at 2-8°C in tightly sealed containers is recommended for long-term stability. This compound is particularly useful for developing novel therapeutic agents and studying structure-activity relationships in medicinal chemistry.

Properties

• CAS Number: 1914-65-4
• Complexity: 200
• IUPAC Name: tetralin-1-carboxylic acid
• InChI: InChI=1S/C11H12O2/c12-11(13)10-7-3-5-8-4-1-2-6-9(8)10/h1-2,4,6,10H,3,5,7H2,(H,12,13)
• InChI Key: VDLWTJCSPSUGOA-UHFFFAOYSA-N
• Exact Mass: 176.083729621
• Molecular Formula: C11H12O2
• Molecular Weight: 176.21
• SMILES: C1CC(C2=CC=CC=C2C1)C(=O)O
• Topological: 37.3
• Monoisotopic Mass: 176.083729621
• Synonyms: 1,2,3,4-Tetrahydro-1-naphthoic acid, 641-736-8, 1914-65-4, 1,2,3,4-tetrahydronaphthalene-1-carboxylic acid, 1-Naphthalenecarboxylic acid, 1,2,3,4-tetrahydro-, 1,2,3,4-Tetrahydro-naphthalene-1-carboxylic acid, Tetralin-1-carboxylic Acid, MFCD02179127, CHEMBL81606, 1,2,3,4-tetrahydro-1-naphthalenecarboxylic acid, 1,2,3,4-Tetrahedro-naphthoic acid, 1,2,3,4-tetrahydronaphthalenecarboxylic acid, MFCD07368364, MFCD07368365, 1-TETRALINCARBOXYLIC ACID, tetrahydronaphthoic acid, (S)-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid, SCHEMBL242244, F2191-0014, SCHEMBL1567657, SCHEMBL2122282, DTXSID80940758, 1,2,3,4-Tetrahedronaphthoic acid, ALBB-023183, BCP08831, BBL104211, BDBM50022451, SBB065730, STL558075, AKOS001452907, AKOS016842282, AB11024, CS-W019746, FS-2878, FT14812, SB44573, SY002157, SY021995, SY107224, DB-018709, ST45016683, T2903, EN300-30407, 1,2,3,4-tetrahydro-1-naphthoic acid, AldrichCPR, 1,2,3,4-tetrahydro-naphthalen-1-carboxylic acid, A816684, AE-842/31479032, Z235361249

Application

1,2,3,4-Tetrahydro-1-naphthoic acid serves as a key building block in pharmaceutical research, particularly for developing cardiovascular and central nervous system drugs. Its tetrahydronaphthalene structure makes it valuable for creating analogs of important pharmacophores. Researchers utilize this compound in studying enzyme inhibition mechanisms and receptor binding interactions. The carboxylic acid functionality allows for straightforward derivatization to esters, amides, and other important functional groups.

Safety and Hazards

GHS Hazard Statements

• H302 (14.3%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (85.7%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (85.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (71.4%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
• H373 (14.3%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

Precautionary Statements

• P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (85.7%)
• Eye Irrit. 2A (85.7%)
• STOT SE 3 (71.4%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.