Atomfair

Awaiting product image

Atomfair Methyl 3-fluoro-5-methylisonicotinate C8H8FNO2 CAS 1803821-90-0

Methyl 3-fluoro-5-methylisonicotinate (CAS No. 1803821-90-0) is a high-purity fluorinated pyridine derivative with the molecular formula C8H8FNO2. This compound, also known as methyl 3-fluoro-5-methylpyridine-4-carboxylate, is a versatile building block in pharmaceutical and agrochemical research. Its unique structure, featuring a fluorine substituent and a methyl ester group on the pyridine ring, makes it valuable for synthesizing bioactive molecules, ligands, and intermediates. The product is rigorously tested for quality (≥95% purity by HPLC) and is supplied in sealed, light-resistant packaging to ensure stability. Ideal for medicinal chemistry, cross-coupling reactions, and heterocyclic compound development.

Category:

Description

Methyl 3-fluoro-5-methylisonicotinate (CAS No. 1803821-90-0) is a high-purity fluorinated pyridine derivative with the molecular formula C8H8FNO2. This compound, also known as methyl 3-fluoro-5-methylpyridine-4-carboxylate, is a versatile building block in pharmaceutical and agrochemical research. Its unique structure, featuring a fluorine substituent and a methyl ester group on the pyridine ring, makes it valuable for synthesizing bioactive molecules, ligands, and intermediates. The product is rigorously tested for quality (≥95% purity by HPLC) and is supplied in sealed, light-resistant packaging to ensure stability. Ideal for medicinal chemistry, cross-coupling reactions, and heterocyclic compound development.

Properties

  • CAS Number: 1803821-90-0
  • Complexity: 174
  • IUPAC Name: methyl 3-fluoro-5-methyl-pyridine-4-carboxylate
  • InChI: InChI=1S/C8H8FNO2/c1-5-3-10-4-6(9)7(5)8(11)12-2/h3-4H,1-2H3
  • InChI Key: NVJYTGPBZODHPT-UHFFFAOYSA-N
  • Exact Mass: 169.05390666
  • Molecular Formula: C8H8FNO2
  • Molecular Weight: 169.15
  • SMILES: CC1=CN=CC(=C1C(=O)OC)F
  • Topological: 39.2
  • Monoisotopic Mass: 169.05390666
  • Synonyms: 1803821-90-0, Methyl 3-fluoro-5-methylisonicotinate, 812-426-1, Methyl 3-fluoro-5-methylpyridine-4-carboxylate, 4-Pyridinecarboxylic acid, 3-fluoro-5-methyl-, methyl ester, SCHEMBL20187531, Methyl3-fluoro-5-methylisonicotinate, MFCD28798350, AKOS037655515, PS-11622, D79934

Application

Methyl 3-fluoro-5-methylisonicotinate serves as a key intermediate in the synthesis of fluorinated pharmaceuticals, particularly kinase inhibitors and CNS-targeting drugs. Its reactive ester group enables facile derivatization, while the fluorine atom enhances metabolic stability in drug candidates. Researchers also utilize it in metal-catalyzed cross-coupling reactions to construct complex heterocycles. Applications extend to agrochemical development, where fluorinated pyridines improve pesticide efficacy.

Safety and Hazards

GHS Hazard Statements

  • H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
  • H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]
  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]
  • H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Acute Tox. 4 (100%)
  • Acute Tox. 4 (100%)
  • Skin Irrit. 2 (100%)
  • Eye Irrit. 2 (100%)
  • Acute Tox. 4 (100%)
  • STOT SE 3 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.

Related products