Description
1-(4-Chloro-2-fluorophenyl)ethan-1-one (CAS No. 175711-83-8) is a high-purity organic compound with the molecular formula C8H6ClFO. This aromatic ketone features a chloro- and fluoro-substituted phenyl ring, making it a valuable intermediate in synthetic organic chemistry and pharmaceutical research. Its IUPAC name is 1-(4-chloro-2-fluorophenyl)ethanone, and it is characterized by excellent stability under standard laboratory conditions. Available in >98% purity (HPLC), this compound is supplied in sealed containers to ensure integrity and longevity. Ideal for researchers developing novel drug candidates, agrochemicals, or specialty materials requiring halogenated aromatic ketones.
Properties
- CAS Number: 175711-83-8
- Complexity: 160
- IUPAC Name: 1-(4-chloro-2-fluoro-phenyl)ethanone
- InChI: InChI=1S/C8H6ClFO/c1-5(11)7-3-2-6(9)4-8(7)10/h2-4H,1H3
- InChI Key: OIGMDNONQJGUCF-UHFFFAOYSA-N
- Exact Mass: 172.0091207
- Molecular Formula: C8H6ClFO
- Molecular Weight: 172.58
- SMILES: CC(=O)C1=C(C=C(C=C1)Cl)F
- Topological: 17.1
- Monoisotopic Mass: 172.0091207
- Synonyms: 175711-83-8, 1-(4-Chloro-2-fluorophenyl)ethanone, 1-(4-Chloro-2-fluorophenyl)ethan-1-one, DTXSID90567213, DTXCID60517987, 605-759-7, 4′-Chloro-2′-fluoroacetophenone, 4-chloro-2-fluoroacetophenone, Ethanone, 1-(4-chloro-2-fluorophenyl)-, MFCD04116328, 1-(4-chloro-2-fluoro-phenyl)-ethanone, 4 inverted exclamation mark -Chloro-2 inverted exclamation mark -fluoroacetophenone, 4/’/’-CHLORO-2/’/’-FLUOROACETOPHENONE, 1-acetyl-4-chloro-2-fluorobenzene, SCHEMBL325429, SCHEMBL25176939, 4-fluoroacetophenone, OIGMDNONQJGUCF-UHFFFAOYSA-N, CL8666, SBB064338, AKOS005063601, AC-1568, FC70095, PS-8659, SY011386, CS-0094504, EN300-123641
Application
1-(4-Chloro-2-fluorophenyl)ethan-1-one serves as a key building block in the synthesis of pharmaceuticals, particularly for anti-inflammatory and CNS-active compounds. Its halogenated structure enables selective functionalization in cross-coupling reactions. Researchers also utilize it in material science for developing liquid crystals or photoactive polymers. The compound’s reactivity makes it suitable for Grignard reactions and nucleophilic substitutions.
Safety and Hazards
GHS Hazard Statements
- H302 (97.5%): Harmful if swallowed [Warning Acute toxicity, oral]
Precautionary Statements
- P264, P270, P301+P317, P330, and P501
Hazard Classes and Categories
- Acute Tox. 4 (97.5%)
If you are interested or have any questions, please contact us at support@atomfair.com
Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.
Reviews
There are no reviews yet.