Description

4-(Trifluoromethoxy)benzenemethanol (CAS No. 1736-74-9) is a high-purity fluorinated aromatic alcohol with the molecular formula C₈H₇F₃O₂. This compound, also known as [4-(trifluoromethoxy)phenyl]methanol, features a benzenemethanol core substituted with a trifluoromethoxy group at the para position, enhancing its reactivity and utility in synthetic applications. Ideal for researchers and scientists, this reagent is rigorously tested for quality, ensuring consistent performance in organic synthesis, pharmaceutical intermediates, and material science. Available in various quantities, it is supplied with detailed analytical certificates (including GC/HPLC, NMR, and MS) to guarantee purity and traceability. Store in a cool, dry place under inert conditions to maintain stability.

Properties

• CAS Number: 1736-74-9
• Complexity: 150
• IUPAC Name: [4-(trifluoromethoxy)phenyl]methanol
• InChI: InChI=1S/C8H7F3O2/c9-8(10,11)13-7-3-1-6(5-12)2-4-7/h1-4,12H,5H2
• InChI Key: ZLSOZAOCYJDPKX-UHFFFAOYSA-N
• Exact Mass: 192.03981395
• Molecular Formula: C8H7F3O2
• Molecular Weight: 192.13
• SMILES: C1=CC(=CC=C1CO)OC(F)(F)F
• Topological: 29.5
• Monoisotopic Mass: 192.03981395
• Synonyms: 4-(trifluoromethoxy)benzenemethanol, 4-(Trifluoromethoxy)benzyl alcohol, 1736-74-9, (4-(Trifluoromethoxy)phenyl)methanol, [4-(Trifluoromethoxy)phenyl]methanol, Benzenemethanol, 4-(trifluoromethoxy)-, p-Trifluoromethoxybenzyl alcohol, 4-(Trifluoromethoxy)benzylalcohol, MFCD00036029, [4-(trifluoromethoxy)phenyl]methan-1-ol, p-trifluoromethoxybenzylalchol, 4-trifluoromethoxybenzyl alcohol, 4-(Trifluoromethoxy)-benzenemethanol; p-(Trifluoromethoxy)-benzyl Alcohol; 4-(Trifluoromethoxy)benzenemethanol; [4-(Trifluoromethoxy)phenyl]methanol, SCHEMBL963834, SCHEMBL1005875, SCHEMBL5183831, SCHEMBL28757636, 4-trifluoromethoxy benzyl alcohol, DTXSID10169637, CHEBI:195150, GHUXMYGGSCUWJD-UHFFFAOYSA-N, p-(trifluoromethoxy)benzyl alcohol, [4-(triluoromethoxy)phenyl]methanol, [4-(Trifluoromethoxy)pheny]methanol, CK1131, SBB063443, AKOS000249058, AC-9760, CS-W010710, FT64470, PS-8337, SDCCGMLS-0066270.P001, [4-(Trifluoromethoxy)phenyl]methanol #, 4-(Trifluoromethoxy)benzyl alcohol, 97%, SY011516, DB-001270, ST50405253, EN300-1932879

Application

4-(Trifluoromethoxy)benzenemethanol is widely used as a key intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty materials. Its trifluoromethoxy group imparts unique electronic and steric properties, making it valuable in drug discovery and medicinal chemistry. This compound is also employed in the development of liquid crystals and advanced polymers due to its aromatic fluorinated structure. Researchers utilize it to introduce trifluoromethoxy-substituted benzyl motifs into target molecules for enhanced bioactivity.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (50%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (50%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.