Description

Fabomotizole Hydrochloride (CAS 173352-39-1) is a high-purity synthetic compound with the molecular formula C₁₅H₂₂ClN₃O₂S, widely utilized in pharmacological research and neurochemical studies. This hydrochloride salt of fabomotizole, also known as Afobazole HCl, exhibits selective anxiolytic properties by modulating sigma-1 receptors and influencing GABAergic systems without inducing sedation or muscle relaxation. Its IUPAC name, 4-[2-[(6-ethoxy-1H-benzimidazol-2-yl)sulfanyl]ethyl]morpholine;hydrochloride, reflects its unique benzimidazole-morpholine hybrid structure. Our product is rigorously tested via HPLC (>98% purity) and complies with ISO 9001 standards, ensuring optimal consistency for in vitro assays, animal studies, and drug development pipelines. Each batch is supplied in tamper-evident vials with comprehensive COA, MSDS, and stability data.

Properties

• CAS Number: 173352-39-1
• Complexity: 315
• IUPAC Name: 4-[2-[(6-ethoxy-1H-benzimidazol-2-yl)sulfanyl]ethyl]morpholine;hydrochloride
• InChI: InChI=1S/C15H21N3O2S.ClH/c1-2-20-12-3-4-13-14(11-12)17-15(16-13)21-10-7-18-5-8-19-9-6-18;/h3-4,11H,2,5-10H2,1H3,(H,16,17);1H
• InChI Key: MYSRFAUFQZYTOV-UHFFFAOYSA-N
• Exact Mass: 343.1121258
• Molecular Formula: C15H22ClN3O2S
• Molecular Weight: 343.9
• SMILES: CCOC1=CC2=C(C=C1)N=C(N2)SCCN3CCOCC3.Cl
• Topological: 75.7
• Monoisotopic Mass: 343.1121258
• Synonyms: 173352-39-1, Afobazole hydrochloride, Fabomotizole hydrochloride, Fabomotizole (hydrochloride), Afobazol HCl, HDO6HX6NZU, 4-(2-((6-Ethoxy-1H-benzo[d]imidazol-2-yl)thio)ethyl)morpholine hydrochloride, SM-346, Afobazol hydrochloride, 4-[2-[(6-ethoxy-1H-benzimidazol-2-yl)sulfanyl]ethyl]morpholine;hydrochloride, Afobazole HCl, 4-(2-((5-ethoxy-1H-benzo[d]imidazol-2-yl)thio)ethyl)morpholine hydrochloride, CM346 hydrochloride, UNII-HDO6HX6NZU, Fabomotizole HCl, Afobazol HCl?, Afobazolehydrochloride, Fabomotizole?hydrochloride, OBENOXAZINE HYDROCHLORIDE, AFOBAZOL MONOHYDROCHLORIDE, AFOBAZOLE MONOHYDROCHLORIDE, DTXSID50938369, APHOBAZOLE MONOHYDROCHLORIDE, GLXC-05466, HMS5086L21, BCP29097, FABOMOTIZOLE MONOHYDROCHLORIDE, HY-14895A, SM 346, AKOS030526652, CS-3264, BS-15652, DA-73291, FABOMOTIZOLE HYDROCHLORIDE [MART.], FABOMOTIZOLE HYDROCHLORIDE [WHO-DD], S2474, FABOMOTIZOLE MONOHYDROCHLORIDE [MART.], D71044, 2-((2-Morpholino)ethylthio)-5-ethoxybenzimidazole, Q27279879, 2-[2-(morpholino)-ethylthio]-5-ethoxy-benzimidazole hydrochloride, 5-ethoxy-2-[2-(mor pholino)-ethylthio]benzimidazole hydrochloride, 1H-BENZIMIDAZOLE, 5-ETHOXY-2-((2-(4-MORPHOLINYL)ETHYL)THIO)-, MONOHYDROCHLORIDE, 1H-BENZIMIDAZOLE, 6-ETHOXY-2-((2-(4-MORPHOLINYL)ETHYL)THIO)-, HYDROCHLORIDE (1:1), 6-Ethoxy-2-{[2-(morpholin-4-yl)ethyl]sulfanyl}-1H-benzimidazole–hydrogen chloride (1/1)

Application

Fabomotizole hydrochloride is primarily investigated for its neuroprotective and anxiolytic effects in preclinical models, particularly in stress-induced disorders and cognitive impairment research. It demonstrates selective affinity for sigma-1 receptors, making it valuable for studying neurotransmitter modulation without benzodiazepine-like side effects. Researchers also explore its potential in mitigating oxidative stress and mitochondrial dysfunction in neurodegenerative diseases.

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