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Atomfair (1R)-(-)-1-Phenylethane-1,2-diol C8H10O2 CAS 16355-00-3

(1R)-(-)-1-Phenylethane-1,2-diol (CAS: 16355-00-3) is a high-purity chiral diol widely used in asymmetric synthesis and pharmaceutical research. This compound, with the molecular formula C8H10O2, serves as a versatile building block for the preparation of enantiomerically pure intermediates, ligands, and catalysts. Its (R)-configuration makes it particularly valuable for stereoselective transformations, including dihydroxylation and reduction reactions. Available in ≥98% purity (HPLC), this product is rigorously tested for quality and consistency, ensuring optimal performance in sensitive applications. Suitable for use in organic synthesis, medicinal chemistry, and material science, it is packaged under inert conditions to maintain stability and shelf life.

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Description

(1R)-(-)-1-Phenylethane-1,2-diol (CAS: 16355-00-3) is a high-purity chiral diol widely used in asymmetric synthesis and pharmaceutical research. This compound, with the molecular formula C8H10O2, serves as a versatile building block for the preparation of enantiomerically pure intermediates, ligands, and catalysts. Its (R)-configuration makes it particularly valuable for stereoselective transformations, including dihydroxylation and reduction reactions. Available in ≥98% purity (HPLC), this product is rigorously tested for quality and consistency, ensuring optimal performance in sensitive applications. Suitable for use in organic synthesis, medicinal chemistry, and material science, it is packaged under inert conditions to maintain stability and shelf life.

Properties

  • CAS Number: 16355-00-3
  • Complexity: 87.3
  • IUPAC Name: (1R)-1-phenylethane-1,2-diol
  • InChI: InChI=1S/C8H10O2/c9-6-8(10)7-4-2-1-3-5-7/h1-5,8-10H,6H2/t8-/m0/s1
  • InChI Key: PWMWNFMRSKOCEY-QMMMGPOBSA-N
  • Exact Mass: 138.068079557
  • Molecular Formula: C8H10O2
  • Molecular Weight: 138.16
  • SMILES: C1=CC=C(C=C1)[C@H](CO)O
  • Topological: 40.5
  • Monoisotopic Mass: 138.068079557
  • Synonyms: (1R)-(-)-1-Phenylethane-1,2-diol, 640-490-9, 16355-00-3, (R)-(-)-1-Phenyl-1,2-ethanediol, (R)-1-phenylethane-1,2-diol, (1R)-1-phenylethane-1,2-diol, (R)-1-Phenyl-1,2-ethanediol, 1,2-Ethanediol, 1-phenyl-, (1R)-, Styrene glycol, (-)-, (-)-Styrene glycol, (R)-(-)-1-Phenylethane-1,2-diol, (R)-STYRENE GLYCOL, (R)-(+)-1-Phenylethane-1,2-diol, UNII-2LZM4B71KF, 2LZM4B71KF, MFCD00064262, r-(-)-1-phenyl-1,2-ethanediol, (R)-phenylethylene glycol, 1,2-Ethanediol, 1-phenyl-, (R)-, (R)-phenylethane-1,2-diol, (R)-(-)-Styrene Glycol, FEH, (-)-PHENYLGLYCOL, SCHEMBL3413766, (R)-(-)-Phenylethylene glycol, SCHEMBL28166688, BDBM36100, CHEBI:231713, STR02743, FD1184, AKOS005146058, AKOS005257757, AC-5683, CS-W016497, (R)-1-PHENYL-2-HYDROXYETHANOL, DB-031271, P1150, (R)-(-)-1-Phenyl-1,2-ethanediol, 99%, EN300-317523, Q27254904, (R)-(-)-1-Phenyl-1,2-ethanediol, purum, >=98.0% (sum of enantiomers, HPLC)

(1R)-(-)-1-Phenylethane-1,2-diol is a key chiral auxiliary in asymmetric synthesis, enabling the production of enantiopure pharmaceuticals and fine chemicals. It is commonly employed as a ligand precursor in transition-metal catalysis and as a resolving agent for racemic mixtures. Researchers also utilize it in the synthesis of bioactive molecules and polymer precursors. Its high enantiomeric purity ensures reliable reproducibility in stereocontrolled reactions.

Safety and Hazards

GHS Hazard Statements

  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Skin Irrit. 2 (100%)
  • Eye Irrit. 2 (100%)
  • STOT SE 3 (100%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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