Description

Methoxyfenozide (CAS 161050-58-4) is a highly selective, non-steroidal ecdysone agonist insecticide with the molecular formula C₂₂H₂₈N₂O₃. This technical-grade active ingredient is specifically designed for agricultural pest management, targeting lepidopteran larvae through precise disruption of their molting process. The compound’s IUPAC name, N’-tert-butyl-N’-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide, reflects its unique benzohydrazide structure with methoxy and dimethyl substitutions that confer exceptional biological activity. Our product is supplied as a high-purity (>98%) white crystalline solid with excellent batch-to-batch consistency, characterized by HPLC and GC analysis. Suitable for formulation into SC, WG, and EC products, this material shows superior rainfastness and photostability for field applications. Each shipment includes comprehensive analytical certificates and is packaged in amber glass or HDPE containers with argon headspace to ensure long-term stability.

Properties

• CAS Number: 161050-58-4
• Complexity: 518
• IUPAC Name: N’-tert-butyl-N’-(3,5-dimethylbenzoyl)-3-methoxy-2-methyl-benzohydrazide
• InChI: InChI=1S/C22H28N2O3/c1-14-11-15(2)13-17(12-14)21(26)24(22(4,5)6)23-20(25)18-9-8-10-19(27-7)16(18)3/h8-13H,1-7H3,(H,23,25)
• InChI Key: QCAWEPFNJXQPAN-UHFFFAOYSA-N
• LogP: log Kow = 3.7
• Exact Mass: 368.20999276
• Molecular Formula: C22H28N2O3
• Molecular Weight: 368.5
• SMILES: CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C(=CC=C2)OC)C)C
• Topological: 58.6
• Monoisotopic Mass: 368.20999276
• Color/Form: White powder
• Melting Point: 206.2 – 208 °C
• Solubility: In DMSO 11, cyclohexanone 9.9, acetone 9
• Synonyms: Methoxyfenozide, 161050-58-4, N’-tert-Butyl-N’-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide, Methoxyphenozide, Benzoic acid, 3-methoxy-2-methyl-, 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide, Intrepid (pesticide), Prodigy, Methoxyfenozide [ISO:ANSI:BSI], DTXSID3032628, UNII-62A22651ZX, CHEBI:38449, HSDB 7936, 62A22651ZX, METHOXYFENOZIDE [MI], METHOXYFENOZIDE [ISO], RG 102398, RH 112485, DTXCID1012628, RH-112485, Methoxyfenozide (ISO:ANSI:BSI), USEPA/OPP Pesticide Code: 121027, N-tert-butyl-N’-(3-methoxy-2-methylbenzoyl)-3,5-dimethylbenzohydrazide, 211236-73-6, 605-245-2, N’-(tert-Butyl )-N’-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide, Intrepid, Runner, 3-Methoxy-2-methylbenzoic acid 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide, 163442-56-6, N-tert-butyl-N’-(3-methoxy-o-toluoyl)-3,5-xylohydrazide, N’-(tert-butyl)-N’-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide, RH-2485, CHEMBL55772, Methoxyfenozide 10 microg/mL in Acetonitrile, RG 102398; RH 112485; RH 2485, RH 2485, MFCD03792750, Methoxyfenozide (Standard), SCHEMBL27595, BCP10196, MSK20363, Tox21_301100, BDBM50128305, 3-Methoxy-2-methylbenzoic acid 2-(3,5-dimethylbenzoyl)-2-tert-butylhydrazide, AKOS015895784, HY-117386R, NCGC00163951-01, NCGC00163951-02, NCGC00163951-03, NCGC00255000-01, DS-16494, DB-241062, HY-117386, CAS-161050-58-4, CS-0065614, NS00000434, C18525, C73059, Methoxyfenozide, PESTANAL(R), analytical standard, Q15632812, N-tert-butyl-N”-(3-methoxy-o-toluoyl)-3,5-xylohydrazide, N”-tert-butyl-N”-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide, N”-(tert-butyl)-N”-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide, N-(3-methoxy-2-methylbenzoyl)-N'(3,5-dimethylbenzoyl)-N’-tert-butylhydrazine, N-(3-methoxy-2-methylbenzoyl)-N’-(3,5-dimethylbenzoyl)-N’-tert-butylhydrazine, Benzoic acid, 3-methoxy-2-methyl-, 2-(3,5-dimethyl-benzoyl)-2-(1,1-dimethylethyl)hydrazide

Application

Methoxyfenozide is extensively used in integrated pest management (IPM) programs for controlling caterpillar pests in fruit orchards, vegetable crops, and row crops. The compound acts as a molting accelerator by selectively binding to ecdysone receptors in target insects. Field studies demonstrate exceptional efficacy against Helicoverpa, Spodoptera, and Plutella species at application rates of 50-100 g ai/ha. Its unique mode of action makes it valuable for resistance management strategies, particularly in Bt crop systems. The material exhibits excellent translaminar activity with minimal impact on beneficial arthropods when used according to label recommendations.

Safety and Hazards

GHS Hazard Statements

• Not Classified

Precautionary Statements

• P273, P391, and P501

Hazard Classes and Categories

• Aquatic Acute 1 (69.9%)
• Aquatic Chronic 1 (69.9%)
• Aquatic Chronic 2 (30.1%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.