Description

6-Amino-3-methylpyridine (CAS No. 1603-41-4) is a high-purity heterocyclic organic compound with the molecular formula C₆H₈N₂. Also known by its IUPAC name 5-methylpyridin-2-amine, this versatile chemical building block features an amino group at the 2-position and a methyl group at the 5-position of the pyridine ring. Our product is rigorously tested to ensure exceptional quality, with typical purity levels ≥98% (GC). Supplied as a white to light yellow crystalline powder, it exhibits excellent solubility in common organic solvents including ethanol, methanol, and dichloromethane. This compound is particularly valuable for pharmaceutical intermediates, agrochemical synthesis, and coordination chemistry applications. Proper storage in a cool, dry place under inert atmosphere is recommended to maintain stability.

Properties

• CAS Number: 1603-41-4
• Complexity: 72.9
• IUPAC Name: 5-methylpyridin-2-amine
• InChI: InChI=1S/C6H8N2/c1-5-2-3-6(7)8-4-5/h2-4H,1H3,(H2,7,8)
• InChI Key: CMBSSVKZOPZBKW-UHFFFAOYSA-N
• Exact Mass: 108.068748264
• Molecular Formula: C6H8N2
• Molecular Weight: 108.14
• SMILES: CC1=CN=C(C=C1)N
• Topological: 38.9
• Monoisotopic Mass: 108.068748264
• Synonyms: 2-Amino-5-methylpyridine, 1603-41-4, 6-Amino-3-picoline, 2-AMINO-5-PICOLINE, 2-Pyridinamine, 5-methyl-, 6-Amino-3-methylpyridine, 5-Methyl-2-aminopyridine, 3-Picoline, 6-amino-, 5-Methyl-2-pyridinamine, 5-Methyl-2-pyridylamine, NSC 1489, NSC 96444, EINECS 216-503-5, BRN 0107050, 8UM54T43WT, DTXSID4029220, AI3-52276, NSC-1489, NSC-96444, DTXCID909220, 5-22-09-00289 (Beilstein Handbook Reference), AMINO-3-METHYLPYRIDINE, 6-, inchi=1/c6h8n2/c1-5-2-3-6(7)8-4-5/h2-4h,1h3,(h2,7,8, 5-METHYLPYRIDIN-2-AMINE, 5-methylpyridin-2-ylamine, 2-amino-5-methyl pyridine, 5-Methyl-pyridin-2-ylamine, MFCD00006328, (5-Methylpyridin-2-yl)amine, CHEMBL61990, pyridine, 2-amino-5-methyl-, LG4, UNII-8UM54T43WT, amino-5-picoline, 6-amino-3 picoline, 2-amino-5methylpyridine, 5-methyl-2-aminopyridin, 5-methylpyridine-2-amine, 2-amino-5-methyl-pyridine, 2-Amino-5-methylpyridine (2-Amino-5-picoline), NCIOpen2_001614, SCHEMBL16868, Pyridine, 2-amino-5-methyl, 5-methyl-pyridin-2-yl-amine, SCHEMBL294508, SCHEMBL424306, SCHEMBL5408467, SCHEMBL10057634, SCHEMBL11270080, SCHEMBL11549086, SCHEMBL21598392, SCHEMBL21598397, NSC1489, 2-Amino-5-methylpyridine, 99%, BCP16835, CS-D0808, NSC96444, STR01239, Tox21_200474, BDBM50091808, RB8006, SBB004353, STK398101, AKOS000119512, AC-4664, FA00539, PS-9284, SDCCGMLS-0066227.P001, NCGC00248645-01, NCGC00258028-01, BP-10235, CAS-1603-41-4, DB-023762, A0732, NS00025220, ST50680980, EN300-19786, 2-Amino-5-methylpyridine;5-Methylpyridin-2-amine, AC-907/25014132, Q27271041, F0001-0574, Z104475374

Application

6-Amino-3-methylpyridine serves as a key intermediate in the synthesis of various pharmaceutical compounds, particularly those targeting central nervous system disorders. Its structural features make it valuable for creating metal-organic frameworks (MOFs) in materials science research. The compound is also utilized in the development of agricultural chemicals and as a ligand in catalytic systems for organic transformations.

Safety and Hazards

GHS Hazard Statements

• H301 (98.3%): Toxic if swallowed [Danger Acute toxicity, oral]
• H311 (95%): Toxic in contact with skin [Danger Acute toxicity, dermal]
• H315 (98.3%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (98.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H331 (70%): Toxic if inhaled [Danger Acute toxicity, inhalation]
• H335 (85%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P262, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P316, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 3 (98.3%)
• Acute Tox. 3 (95%)
• Skin Irrit. 2 (98.3%)
• Eye Irrit. 2 (98.3%)
• Acute Tox. 3 (70%)
• STOT SE 3 (85%)

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