Description

2,3-Difluoropyridine (CAS No. 1513-66-2) is a high-purity fluorinated pyridine derivative with the molecular formula C₅H₃F₂N. This heterocyclic compound is widely utilized in pharmaceutical, agrochemical, and materials science research due to its unique electronic and steric properties conferred by the fluorine substituents. Our product is synthesized under strict quality control measures, ensuring ≥98% purity (GC) and is available in various quantities to suit laboratory-scale and industrial applications. It is supplied in sealed, light-resistant containers under inert atmosphere to maintain stability. 2,3-Difluoropyridine serves as a versatile building block for nucleophilic substitution reactions, cross-coupling chemistry, and the development of fluorinated bioactive molecules. Suitable for use in medicinal chemistry, catalyst design, and electronic materials. Handle with appropriate precautions in a well-ventilated environment.

Properties

• CAS Number: 1513-66-2
• Complexity: 76.8
• IUPAC Name: 2,3-difluoropyridine
• InChI: InChI=1S/C5H3F2N/c6-4-2-1-3-8-5(4)7/h1-3H
• InChI Key: OGVLEPMNNPZAPS-UHFFFAOYSA-N
• Exact Mass: 115.02335542
• Molecular Formula: C5H3F2N
• Molecular Weight: 115.08
• SMILES: C1=CC(=C(N=C1)F)F
• Topological: 12.9
• Monoisotopic Mass: 115.02335542
• Synonyms: 2,3-Difluoropyridine, 1513-66-2, DTXSID70382486, DTXCID90333511, 675-555-0, PYRIDINE, 2,3-DIFLUORO-, 2,3-Difluoro pyridine, difluoropyridine, MFCD04114143, 2,3-dibromopyridin, 2,3-difluorpyridine, 2,3-bis(fluoranyl)pyridine, 2,3-Difluoropyridine, 95%, Pyridine, 2,?3-?difluoro-, SCHEMBL226935, SCHEMBL255507, SCHEMBL407220, SCHEMBL1740303, BCP22116, AC-336, BBL102620, STL556423, AKOS005063473, CS-W016604, FD16119, PS-9233, SB11511, DB-005121, D3892, EN300-86192, A809167

Application

2,3-Difluoropyridine is primarily employed as a key intermediate in pharmaceutical synthesis, particularly for developing fluorinated drug candidates with enhanced metabolic stability and membrane permeability. In material science, it functions as a precursor for liquid crystals and electronic materials due to its strong dipole moment and electron-withdrawing characteristics. The compound also finds use in agrochemical research for creating novel pesticides and herbicides with improved environmental profiles.

Safety and Hazards

GHS Hazard Statements

• H226 (97.9%): Flammable liquid and vapor [Warning Flammable liquids]
• H302 (83.3%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (14.6%): Causes skin irritation [Warning Skin corrosion/irritation]
• H318 (83.3%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
• H319 (14.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (12.5%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
• H400 (83.3%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

Precautionary Statements

• P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P391, P403+P233, P403+P235, P405, and P501

Hazard Classes and Categories

• Flam. Liq. 3 (97.9%)
• Acute Tox. 4 (83.3%)
• Skin Irrit. 2 (14.6%)
• Eye Dam. 1 (83.3%)
• Eye Irrit. 2 (14.6%)
• Aquatic Acute 1 (83.3%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.