Description

2-Amino-3-methoxybenzonitrile (CAS No. 148932-68-7) is a high-purity organic compound with the molecular formula C₈H₈N₂O. This fine chemical is characterized by its amino and methoxy functional groups attached to a benzonitrile core, making it a valuable intermediate in pharmaceutical and agrochemical synthesis. Ideal for researchers and scientists, our product is rigorously tested to ensure ≥98% purity (HPLC) and is supplied in sealed, light-resistant packaging to maintain stability. Suitable for use in coupling reactions, heterocyclic synthesis, and as a building block for bioactive molecules. Available in quantities ranging from grams to kilograms to meet both lab-scale and industrial needs.

Properties

• CAS Number: 148932-68-7
• Complexity: 172
• IUPAC Name: 2-amino-3-methoxy-benzonitrile
• InChI: InChI=1S/C8H8N2O/c1-11-7-4-2-3-6(5-9)8(7)10/h2-4H,10H2,1H3
• InChI Key: KLCPAKMBBMVXMD-UHFFFAOYSA-N
• Exact Mass: 148.063662883
• Molecular Formula: C8H8N2O
• Molecular Weight: 148.16
• SMILES: COC1=CC=CC(=C1N)C#N
• Topological: 59
• Monoisotopic Mass: 148.063662883
• Synonyms: 2-amino-3-methoxybenzonitrile, 148932-68-7, DTXSID70473681, DTXCID10424495, 834-055-4, MFCD09744022, 2-Amino-3-Methoxy benzonitrile, Benzonitrile, 2-amino-3-methoxy-, SCHEMBL1622431, KLCPAKMBBMVXMD-UHFFFAOYSA-N, AKOS006331883, CS-W021551, GS-4535, SY035950, DB-049988, EN300-188391, Z1198221994

Application

2-Amino-3-methoxybenzonitrile serves as a versatile precursor in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and other heterocyclic compounds. Its reactive amino and nitrile groups enable participation in condensation and cyclization reactions. Researchers also utilize it in material science for designing functionalized aromatic polymers. The methoxy group enhances solubility in organic solvents, facilitating reaction optimization.

Safety and Hazards

GHS Hazard Statements

• H302+H312+H332 (50%): Harmful if swallowed, in contact with skin or if inhaled [Warning Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]
• H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]
• H312 (50%): Harmful in contact with skin [Warning Acute toxicity, dermal]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H332 (50%): Harmful if inhaled [Warning Acute toxicity, inhalation]
• H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (50%)
• Acute Tox. 4 (50%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• Acute Tox. 4 (50%)
• STOT SE 3 (100%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.