Description

2-Fluorobenzene-1,4-diamine (CAS No. 14791-78-7) is a high-purity aromatic diamine compound with the molecular formula C₆H₇FN₂. This specialized chemical features a fluorine substituent at the 2-position of the benzene ring, adjacent to one of the amine groups, creating unique electronic and steric properties. The compound is supplied as a crystalline solid with typical purity ≥98% (HPLC), making it ideal for research and industrial applications requiring precise molecular architecture.

This fluorinated diamine is particularly valuable as a building block in pharmaceutical synthesis, materials science, and advanced polymer chemistry. Its bifunctional nature allows for incorporation into polyimides, polyamides, and other high-performance polymers where the fluorine substitution can impart enhanced thermal stability, chemical resistance, and modified electronic characteristics. The compound should be stored under inert atmosphere at 2-8°C to maintain stability.

Key specifications include: Molecular Weight: 126.14 g/mol, Melting Point: 98-102°C, Density: 1.25 g/cm³. Available in research quantities from 100mg to 100g with custom bulk quantities available upon request. All batches are accompanied by comprehensive analytical data including ¹H NMR, HPLC, and mass spectrometry reports.

Properties

• CAS Number: 14791-78-7
• Complexity: 97.1
• IUPAC Name: 2-fluorobenzene-1,4-diamine
• InChI: InChI=1S/C6H7FN2/c7-5-3-4(8)1-2-6(5)9/h1-3H,8-9H2
• InChI Key: FXFTWEVIIHVHDS-UHFFFAOYSA-N
• Exact Mass: 126.05932639
• Molecular Formula: C6H7FN2
• Molecular Weight: 126.13
• SMILES: C1=CC(=C(C=C1N)F)N
• Topological: 52
• Monoisotopic Mass: 126.05932639
• Synonyms: 2-fluorobenzene-1,4-diamine, 14791-78-7, 2-FLUORO-BENZENE-1,4-DIAMINE, 1,4-Benzenediamine, 2-fluoro-, MFCD09955618, NSC402988, 3-fluoro-4-aminoaniline, 2,5-diaminofluoroben-zene, SCHEMBL33738, DTXSID50323079, FXFTWEVIIHVHDS-UHFFFAOYSA-N, AKOS009342327, DS-4233, MB08293, NSC-402988, DB-063739, CS-0157059, O10786

Application

2-Fluorobenzene-1,4-diamine serves as a key intermediate in the synthesis of fluorinated polyimide materials for high-temperature electronic applications. The compound is utilized in pharmaceutical research for developing novel tyrosine kinase inhibitors and other bioactive molecules. Its unique structure makes it valuable for creating advanced materials with tailored dielectric properties for microelectronics applications.

Safety and Hazards

GHS Hazard Statements

• H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
• H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

Precautionary Statements

• P264, P264+P265, P270, P280, P301+P317, P305+P354+P338, P317, P330, and P501

Hazard Classes and Categories

• Acute Tox. 4 (100%)
• Eye Dam. 1 (100%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.