Description

Thymine Riboside (5-Methyluridine) is a high-purity nucleoside derivative widely utilized in biochemical and pharmaceutical research. This compound, with the molecular formula C₁₀H₁₄N₂O₆, serves as a critical building block for nucleic acid synthesis and modification studies. As a modified uridine analog, it features a methyl group at the 5-position of the pyrimidine ring, making it valuable for investigating RNA structure, function, and epigenetic modifications. Our product is rigorously tested for purity and stability, ensuring reliable performance in enzymatic assays, oligonucleotide synthesis, and metabolic pathway studies. Available in various quantities to suit research needs, Thymine Riboside is an essential reagent for molecular biologists, chemists, and drug discovery scientists.

Properties

• CAS Number: 1463-10-1
• Complexity: 409
• IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione
• InChI: InChI=1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1
• InChI Key: DWRXFEITVBNRMK-JXOAFFINSA-N
• Exact Mass: 258.08518617
• Molecular Formula: C10H14N2O6
• Molecular Weight: 258.23
• SMILES: CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
• Topological: 119
• Monoisotopic Mass: 258.08518617
• Physical Description: Solid
• Melting Point: 183 – 187 °C
• Synonyms: 5-Methyluridine, 1463-10-1, Ribothymidine, Thymine riboside, Uridine, 5-methyl-, Ribosylthymine, ribosylthymidine, 1-(beta-D-ribofuranosyl)thymine, CHEBI:45996, EINECS 215-973-9, ZS1409014A, THYMINE RIBOSIDE [MI], DTXSID20163348, THYMINE RIBOSIDE, (-)-, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione, PYRIMIDINEDIONE, 5-METHYL-1-.BETA.-D-RIBOFURANOSYL-, 1-.BETA.-D-RIBOFURANOSYLTHYMINE 2,4(1H,3H)-PYRIMIDINEDIONE, 5-METHYL-1-.BETA.-D-RIBOFURANOSYL-, 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione, DTXCID9085839, PYRIMIDINEDIONE, 5-METHYL-1-BETA-D-RIBOFURANOSYL-, 1-BETA-D-RIBOFURANOSYLTHYMINE 2,4(1H,3H)-PYRIMIDINEDIONE, 5-METHYL-1-BETA-D-RIBOFURANOSYL-, 215-973-9, beta-D-Ribofuranoside, Thymine ribofuranoside, MFCD00006535, 5-methyl-Uridine, 5-Methyl Uridine, 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione, 1-((2R,3R,4S,5R)-TETRAHYDRO-3,4-DIHYDROXY-5-(HYDROXYMETHYL)FURAN-2-YL)-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione, 1-[(4S,2R,3R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,3-dihydropyrimidine-2,4-dione, 5MU-5MU-5MU, UNII-ZS1409014A, 38T, 5-methyl-d-uridine, Thymine ribonucleoside, beta-delta-Ribofuranoside, 5-Methyluridine, 97%, bmse000759, Epitope ID:141497, 1-b-D-Ribofuranosylthymine, SCHEMBL29298, b-D-Ribofuranoside thymine-1, .beta.-D-Ribofuranosylthymine, CHEMBL106175, SCHEMBL5888560, 1-.beta.-D-Ribofuranosylthymine, CHEBI:30821, 1-beta-delta-Ribofuranosylthymine, MSK6918, beta-delta-Ribofuranoside thymine-1, .beta.-D-Ribofuranoside, thymine-1, s6156, STL507242, thymine-1 beta-D-Ribofuranosylthymine, AKOS015896830, AC-8172, CS-W010160, HY-W009444, NM04922, thymine-1 beta-delta-Ribofuranosylthymine, BP-58644, DS-18476, PD099507, DB-030334, DB-306748, M1405, NS00024786, EN300-2009864, Q425078, Z3037473449, 5-methyl-1-beta-D-ribofuranosyl-2,4(1H,3H)-Pyrimidinedione, 2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-.beta.-D-ribofuranosyl-, 5-methyl-1-beta-delta-ribofuranosyl-2,4(1H,3H)-Pyrimidinedione

Thymine Riboside is primarily used in RNA research as a modified nucleoside to study post-transcriptional modifications and tRNA function. It serves as a precursor in the synthesis of modified oligonucleotides for probing RNA-protein interactions. Additionally, this compound is valuable in metabolic studies investigating nucleotide salvage pathways and epigenetic regulation.

Safety and Hazards

GHS Hazard Statements

• H315 (33.3%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (33.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (33.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (33.3%)
• Eye Irrit. 2A (33.3%)
• STOT SE 3 (33.3%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.