Description

1,3-Dioxoisoindolin-2-yl 4-(trifluoromethyl)benzoate (CAS No. 1441984-36-6) is a high-purity organic compound with the molecular formula C₁₆H₈F₃NO₄. This specialized chemical features a 1,3-dioxoisoindolin-2-yl (phthalimide) moiety esterified with a 4-(trifluoromethyl)benzoate group, offering unique reactivity for advanced synthetic applications. The presence of the electron-withdrawing trifluoromethyl group enhances its utility in nucleophilic substitution reactions and as a building block for pharmaceuticals, agrochemicals, and materials science. This compound is supplied as a crystalline solid with ≥95% purity (HPLC), rigorously tested for consistency and stability. Ideal for researchers in medicinal chemistry, it serves as a versatile intermediate for developing bioactive molecules, particularly those targeting fluorinated aromatic systems. Store under inert conditions at 2-8°C to maintain integrity.

Properties

• CAS Number: 1441984-36-6
• Complexity: 516
• IUPAC Name: (1,3-dioxoisoindolin-2-yl) 4-(trifluoromethyl)benzoate
• InChI: InChI=1S/C16H8F3NO4/c17-16(18,19)10-7-5-9(6-8-10)15(23)24-20-13(21)11-3-1-2-4-12(11)14(20)22/h1-8H
• InChI Key: ZBHYVSSLPUTOLC-UHFFFAOYSA-N
• Exact Mass: 335.04054222
• Molecular Formula: C16H8F3NO4
• Molecular Weight: 335.23
• SMILES: C1=CC=C2C(=C1)C(=O)N(C2=O)OC(=O)C3=CC=C(C=C3)C(F)(F)F
• Topological: 63.7
• Monoisotopic Mass: 335.04054222
• Synonyms: 1,3-Dioxoisoindolin-2-yl 4-(trifluoromethyl)benzoate, 1441984-36-6, H41876, EN300-6516175, 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 4-(trifluoromethyl)benzoate

Application

1,3-Dioxoisoindolin-2-yl 4-(trifluoromethyl)benzoate is primarily employed as a key intermediate in the synthesis of fluorinated pharmaceutical compounds, leveraging its trifluoromethyl group for enhanced metabolic stability. It finds use in peptide coupling reactions and as a protecting group for amines in multistep organic syntheses. Researchers also utilize it to develop novel materials with tailored electronic properties, owing to its aromatic and electron-deficient characteristics.

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.