Description

Methyl 6-fluoropyridine-3-carboxylate (CAS No. 1427-06-1) is a high-purity fluorinated pyridine derivative with the molecular formula C₇H₆FNO₂. This compound is a versatile building block in organic synthesis, particularly in pharmaceutical and agrochemical research. Its structure features a fluorine substituent at the 6-position and a methyl ester group at the 3-position of the pyridine ring, enabling selective reactivity for cross-coupling, nucleophilic substitution, and other transformations. Suitable for use in medicinal chemistry, this reagent is rigorously tested for quality and consistency, ensuring optimal performance in your experiments. Available in various quantities, it is packaged under inert conditions to maintain stability and purity.

Properties

• CAS Number: 1427-06-1
• Complexity: 151
• IUPAC Name: methyl 6-fluoropyridine-3-carboxylate
• InChI: InChI=1S/C7H6FNO2/c1-11-7(10)5-2-3-6(8)9-4-5/h2-4H,1H3
• InChI Key: HLYBWNNPVXFCPZ-UHFFFAOYSA-N
• Exact Mass: 155.03825660
• Molecular Formula: C7H6FNO2
• Molecular Weight: 155.13
• SMILES: COC(=O)C1=CN=C(C=C1)F
• Topological: 39.2
• Monoisotopic Mass: 155.03825660
• Synonyms: 1427-06-1, Methyl 6-fluoropyridine-3-carboxylate, DTXSID10548564, DTXCID90499348, 634-321-8, Methyl 6-fluoronicotinate, 6-Fluoronicotinic acid methyl ester, MFCD03095098, 3-PYRIDINECARBOXYLIC ACID, 6-FLUORO-, METHYL ESTER, Methyl6-fluoropyridine-3-carboxylate, SCHEMBL1468486, HLYBWNNPVXFCPZ-UHFFFAOYSA-, HLYBWNNPVXFCPZ-UHFFFAOYSA-N, 6-Fluoro-nicotinic acid methyl ester, AKOS015891499, CS-W008583, AC-33356, AS-14960, FM104635, SY022281, DB-027645, M2724, Methyl 6-fluoropyridine-3-carboxylate, 97%, EN300-187558, 6-Fluoropyridine-3-carboxylic Acid Methyl Ester, Z1255446614, InChI=1/C7H6FNO2/c1-11-7(10)5-2-3-6(8)9-4-5/h2-4H,1H3

Application

Methyl 6-fluoropyridine-3-carboxylate is widely used as an intermediate in the synthesis of bioactive molecules, including pharmaceuticals and agrochemicals. Its fluorinated pyridine core is valuable for designing kinase inhibitors, antimicrobial agents, and other therapeutic compounds. Researchers also employ it in cross-coupling reactions to introduce fluorinated heterocycles into complex molecular architectures.

Safety and Hazards

GHS Hazard Statements

• H302 (97.6%): Harmful if swallowed [Warning Acute toxicity, oral]
• H318 (95.1%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

Precautionary Statements

• P264, P264+P265, P270, P280, P301+P317, P305+P354+P338, P317, P330, and P501

Hazard Classes and Categories

• Acute Tox. 4 (97.6%)
• Eye Dam. 1 (95.1%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.