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Atomfair Piperazine Hexahydrate C4H22N2O6 CAS 142-63-2

Piperazine Hexahydrate (CAS No. 142-63-2) is a high-purity chemical compound with the molecular formula C4H22N2O6, widely utilized in pharmaceutical, veterinary, and research applications. This crystalline solid is a hydrated form of piperazine, offering enhanced solubility and stability for precise formulations. It serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly as an impurity reference standard (e.g., Trimetazidine Dihydrochloride Impurity G). Certified to meet European Pharmacopoeia (EP) and analytical standards, our product ensures consistency for HPLC, LC-MS, and other analytical techniques. Packaged under controlled conditions to maintain integrity, it is ideal for laboratories requiring reliable, traceable…

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Description

Piperazine Hexahydrate (CAS No. 142-63-2) is a high-purity chemical compound with the molecular formula C4H22N2O6, widely utilized in pharmaceutical, veterinary, and research applications. This crystalline solid is a hydrated form of piperazine, offering enhanced solubility and stability for precise formulations. It serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly as an impurity reference standard (e.g., Trimetazidine Dihydrochloride Impurity G). Certified to meet European Pharmacopoeia (EP) and analytical standards, our product ensures consistency for HPLC, LC-MS, and other analytical techniques. Packaged under controlled conditions to maintain integrity, it is ideal for laboratories requiring reliable, traceable materials.

Properties

  • CAS Number: 142-63-2
  • Complexity: 26.5
  • IUPAC Name: piperazine;hexahydrate
  • InChI: InChI=1S/C4H10N2.6H2O/c1-2-6-4-3-5-1;;;;;;/h5-6H,1-4H2;6*1H2
  • InChI Key: AVRVZRUEXIEGMP-UHFFFAOYSA-N
  • Exact Mass: 194.14778643
  • Molecular Formula: C4H22N2O6
  • Molecular Weight: 194.23
  • SMILES: C1CNCCN1.O.O.O.O.O.O
  • Topological: 30.1
  • Monoisotopic Mass: 194.14778643
  • Synonyms: Piperazine hexahydrate, 142-63-2, Arthriticine, Piperazine, hexahydrate, Vermisol, Parid, USAF A-3803, Diethylenediamine hexahydrate, UNII-P3M07B8U64, Vermyl (TN), AI3-26675, P3M07B8U64, DTXSID50161918, 1,4-PIPERAZINE HEXAHYDRATE, PIPERAZINE HEXAHYDRATE [II], PIPERAZINE HEXAHYDRATE [MI], PIPERAZINE HYDRATE [MART.], PIPERAZINE, HYDRATE (1:6), PIPERAZINE HEXAHYDRATE [VANDF], PIPERAZINE HEXAHYDRATE [WHO-DD], PIPERAZINE HEXAHYDRATE (II), PIPERAZINE HYDRATE (MART.), Vermyl, DTXCID3084409, 604-300-8, arpezine, arpezine (van), piperazine;hexahydrate, MFCD00149389, PIPERAZINE (HEXAHYDRATE), C4H22N2O6, Trimetazidine Dihydrochloride Imp. G (EP); Trimetazidine Imp. G (EP); Piperazine Hexahydrate; Trimetazidine Dihydrochloride Imp. G (EP) as Hexahydrate; Trimetazidine Dihydrochloride Impurity G as Hexahydrate; Trimetazidine Impurity G as Hexahydrate, SCHEMBL580602, HY-B0912A, AKOS000121857, CS-7631, LS-13032, Piperazine hexahydrate, analytical standard, ST50406165, D08381, Q3905511, Piperazine hydrate, European Pharmacopoeia (EP) Reference Standard, piperazine, hydrate, hydrate, hydrate, hydrate, hydrate, hydrate

Piperazine Hexahydrate is primarily employed as an anthelmintic agent in veterinary medicine to treat parasitic infections. In pharmaceuticals, it acts as a building block for synthesizing APIs and is critical in impurity profiling (e.g., Trimetazidine Impurity G). Researchers leverage its stability in biochemical assays and as a buffering agent. Its solubility also makes it suitable for diagnostic reagent formulations.

Safety and Hazards

GHS Hazard Statements

  • H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
  • H317: May cause an allergic skin reaction [Warning Sensitization, Skin]
  • H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]
  • H361fd: Suspected of damaging fertility; Suspected of damaging the unborn child [Warning Reproductive toxicity]
  • H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]
  • H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

Precautionary Statements

  • P203, P233, P260, P261, P264, P270, P271, P272, P280, P284, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P308+P316, P316, P318, P319, P321, P333+P317, P342+P316, P362+P364, P363, P403, P405, and P501

Hazard Classes and Categories

  • Skin corrosion – category 1B
  • Specific target organ toxicity – category 1
  • Specific target organ toxicity – category 2
  • Reproductive toxicity – category 2
  • Respiratory sensitisation – category 1
  • Skin sensitisation – category 1

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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