Get FREE SHIPPING when you spend $99 or more | ATOMFAIR

Awaiting product image

Atomfair tert-Butyl ((3R,5R)-5-fluoropiperidin-3-yl)carbamate C10H19FN2O2 CAS 1363378-07-7

tert-Butyl ((3R,5R)-5-fluoropiperidin-3-yl)carbamate (CAS No. 1363378-07-7) is a high-purity fluorinated piperidine derivative with the molecular formula C10H19FN2O2. This chiral compound, featuring a tert -butoxycarbonyl (Boc) protecting group, is a valuable intermediate in pharmaceutical synthesis and medicinal chemistry research. Its stereospecific (3R,5R) configuration ensures precise reactivity in asymmetric synthesis. Ideal for peptide modifications, drug discovery, and bioactive molecule development, this compound is supplied as a white to off-white crystalline powder with ≥95% purity (HPLC). Store under inert conditions at 2-8°C for optimal stability. Suitable for use in NMR, LC-MS, and other analytical techniques.

Category:

Description

tert-Butyl ((3R,5R)-5-fluoropiperidin-3-yl)carbamate (CAS No. 1363378-07-7) is a high-purity fluorinated piperidine derivative with the molecular formula C10H19FN2O2. This chiral compound, featuring a tert-butoxycarbonyl (Boc) protecting group, is a valuable intermediate in pharmaceutical synthesis and medicinal chemistry research. Its stereospecific (3R,5R) configuration ensures precise reactivity in asymmetric synthesis. Ideal for peptide modifications, drug discovery, and bioactive molecule development, this compound is supplied as a white to off-white crystalline powder with ≥95% purity (HPLC). Store under inert conditions at 2-8°C for optimal stability. Suitable for use in NMR, LC-MS, and other analytical techniques.

Properties

  • CAS Number: 1363378-07-7
  • Complexity: 228
  • IUPAC Name: tert-butyl N-[(3R,5R)-5-fluoro-3-piperidyl]carbamate
  • InChI: InChI=1S/C10H19FN2O2/c1-10(2,3)15-9(14)13-8-4-7(11)5-12-6-8/h7-8,12H,4-6H2,1-3H3,(H,13,14)/t7-,8-/m1/s1
  • InChI Key: ACHGEWOGBWGEEL-HTQZYQBOSA-N
  • Exact Mass: 218.14305602
  • Molecular Formula: C10H19FN2O2
  • Molecular Weight: 218.27
  • SMILES: CC(C)(C)OC(=O)N[C@@H]1C[C@H](CNC1)F
  • Topological: 50.4
  • Monoisotopic Mass: 218.14305602
  • Synonyms: 1363378-07-7, tert-Butyl ((3R,5R)-5-fluoropiperidin-3-yl)carbamate, tert-butyl N-[(3R,5R)-5-fluoropiperidin-3-yl]carbamate, (3R,5R)-3-(Boc-Amino)-5-fluoropiperidine, Carbamic acid, N-[(3R,5R)-5-fluoro-3-piperidinyl]-, 1,1-dimethylethyl ester, (3R,4R)-rel-3-(Boc-amino)-5-fluoropiperidine, MFCD23105836, 2414303-66-3, rel-(3r,4r)-3-(boc-amino)-5-fluoropiperidine, SCHEMBL21563530, DTXSID601142859, AKOS025289999, PB38917, AS-51703, DB-144500, CS-0048000, P13330, EN300-7150130, tert-butyl (3R,5R)-5-fluoropiperidin-3-ylcarbamate, tert-Butyl((3R,5R)-5-fluoropiperidin-3-yl)carbamate, Rel-tert-butyl ((3R,5R)-5-fluoropiperidin-3-yl)carbamate

Application

This compound serves as a key chiral building block in the synthesis of fluorinated pharmaceutical agents, particularly protease inhibitors and kinase modulators. It is utilized in peptide chemistry for introducing fluorinated piperidine motifs to enhance metabolic stability. Researchers employ it in the development of CNS-targeting drugs due to its ability to improve blood-brain barrier penetration. The Boc-protected amine allows for selective deprotection in multi-step synthetic routes.

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.

Related products