Description

2-Bromo-3-fluorobenzoic acid (CAS No. 132715-69-6) is a high-purity halogenated benzoic acid derivative with the molecular formula C₇H₄BrFO₂. This compound is a valuable building block in organic synthesis, particularly in pharmaceutical and agrochemical research. The presence of both bromine and fluorine substituents on the aromatic ring enhances its reactivity, making it an ideal intermediate for cross-coupling reactions, nucleophilic substitutions, and other functionalization processes. Our product is rigorously tested to ensure ≥98% purity (HPLC) and is supplied as a white to off-white crystalline powder. Suitable for use in medicinal chemistry, material science, and as a precursor for advanced chemical synthesis. Store in a cool, dry place under inert conditions to maintain stability.

Properties

• CAS Number: 132715-69-6
• Complexity: 163
• IUPAC Name: 2-bromo-3-fluoro-benzoic acid
• InChI: InChI=1S/C7H4BrFO2/c8-6-4(7(10)11)2-1-3-5(6)9/h1-3H,(H,10,11)
• InChI Key: KQRCBMPPEPNNDS-UHFFFAOYSA-N
• Exact Mass: 217.93787
• Molecular Formula: C7H4BrFO2
• Molecular Weight: 219.01
• SMILES: C1=CC(=C(C(=C1)F)Br)C(=O)O
• Topological: 37.3
• Monoisotopic Mass: 217.93787
• Synonyms: 2-Bromo-3-fluorobenzoic acid, 132715-69-6, DTXSID50307157, DTXCID80258284, 630-221-3, Benzoic acid, 2-bromo-3-fluoro-, MFCD01569398, 2-bromo-3-fluoro-benzoic acid, 2-Bromo-3-fluorobenzoicacid, 3-fluoro-2-bromo benzoic acid, NSC190303, SCHEMBL394187, KQRCBMPPEPNNDS-UHFFFAOYSA-N, SBB062989, AKOS005063818, AC-1212, CS-W001156, DS-0455, FB38482, NSC-190303, PS-7894, SY003121, 2-Bromo-3-fluorobenzoic acid, AldrichCPR, DB-008171, B3722, EN300-106825, Z1269235363

Application

2-Bromo-3-fluorobenzoic acid is widely used as a key intermediate in the synthesis of bioactive molecules, including pharmaceuticals and agrochemicals. Its halogenated aromatic structure facilitates Suzuki-Miyaura and Buchwald-Hartwig coupling reactions for constructing complex heterocycles. Researchers also employ it in the development of fluorinated liquid crystals and specialty polymers. The compound’s reactivity makes it valuable for introducing fluorine-containing motifs into target molecules.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (87.5%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• STOT SE 3 (87.5%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.