Description

Methyl 5-chloropyridine-2-carboxylate (CAS No. 132308-19-1) is a high-purity organic compound with the molecular formula C₇H₆ClNO₂. This ester derivative of 5-chloropyridine-2-carboxylic acid is a versatile building block in pharmaceutical and agrochemical synthesis. Its IUPAC name is methyl 5-chloropyridine-2-carboxylate, and it is also known by synonyms such as Methyl 5-Chloropicolinate. This compound is characterized by its clear to pale yellow appearance and is typically supplied as a crystalline solid or in solution. It is highly stable under recommended storage conditions (2-8°C, inert atmosphere) and is suitable for use in nucleophilic substitution reactions, cross-coupling reactions, and as a precursor for heterocyclic scaffolds. Ideal for researchers in medicinal chemistry and material science, this product is rigorously tested for purity (≥98% by HPLC or GC) and consistency.

Properties

• CAS Number: 132308-19-1
• Complexity: 151
• IUPAC Name: methyl 5-chloropyridine-2-carboxylate
• InChI: InChI=1S/C7H6ClNO2/c1-11-7(10)6-3-2-5(8)4-9-6/h2-4H,1H3
• InChI Key: QHFFLLBWCXVJGO-UHFFFAOYSA-N
• Exact Mass: 171.0087061
• Molecular Formula: C7H6ClNO2
• Molecular Weight: 171.58
• SMILES: COC(=O)C1=NC=C(C=C1)Cl
• Topological: 39.2
• Monoisotopic Mass: 171.0087061
• Synonyms: 132308-19-1, Methyl 5-chloropyridine-2-carboxylate, 5-CHLOROPYRIDINE-2-CARBOXYLIC ACID METHYL ESTER, methyl 5-chloro-2-pyridinecarboxylate, Methyl 5-Chloropicolinate, 2-Pyridinecarboxylic acid, 5-chloro-, methyl ester, MFCD09702466, 5-chloro-pyridine-2-carboxylic acid methyl ester, SCHEMBL769167, SCHEMBL7958712, 5-CHLORO-2-PYRIDINECARBOXYLIC ACID METHYL ESTER, DTXSID10461547, QHFFLLBWCXVJGO-UHFFFAOYSA-N, BBL101980, SBB088547, STL555777, AKOS006230354, AB51080, CS-W018846, EE-0710, NC66914, SY031483, 5-CHLOROPICOLINIC ACID METHYL ESTER, DB-081700, EN300-51234

Application

Methyl 5-chloropyridine-2-carboxylate is widely used as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and agrochemicals. It serves as a precursor for the development of pyridine-based ligands and catalysts in transition-metal-catalyzed reactions. Researchers utilize this compound in the construction of complex heterocycles for drug discovery, particularly in kinase inhibitor and antiviral agent development. Its reactive chlorine and ester functional groups enable further derivatization via Suzuki-Miyaura coupling or ester hydrolysis.

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.